The panel of assays in the TaqMan® Array 96-well Human Tumor Metastasis Plate targets genes for many tumor suppressor and metastasis suppressor genes. The panel includes genes from the families: MMPs (matrix metalloproteinases); RB (retinoblastoma); and TIMPs (tissue inhibitor of metalloproteinases). Also included are proto-oncogenes, oncogenes, and genes with roles in tumorigenesis and angiogenesis. Additional genes are involved in cell mobility, cell survival, and apoptosis.
APC, BRMS1, CASP8, CCL7, CD44, CD82, CDH1, CDKN2A, CEACAM1, CTBP1, CTNNA1, CTSK, CXCL12, CXCR4, DAPK1, DCC, EPHB2, ERBB2, ETV4, FAT, FGF2, FGFR4, FN1, FXYD5, GNRH1, HGF, HPSE, HRAS, HTATIP2, IGF1, IL18, IL1B, ITGB3, KISS1, KISS1R, KRAS, LAMB1, LYPD3, MCAM, MET, MGAT5, MMP1, MMP10, MMP14, MMP2, MMP3, MMP7, MMP9, MTA1, M...
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18S, GAPDH, GUSB, HPRT1
Metastasis is a complex series of steps in which cancer cells leave the original tumor site and migrate to other parts of the body via the bloodstream or the lymphatic system. To do so, malignant cells break away from the primary tumor and degrade protein ...
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