Panel Description

The panel of assays in the TaqMan® Array 96-well Human Diabetes Plate targets genes that regulate the expression of insulin in the pancreatic beta cells, as well as genes which play a role in insulin resistance. Additional genes on the panel include transcription factors, signal transduction proteins, transporters, and receptors associated with diabetes. Also on the panel are genes associated with obesity and maintenance of blood sugar levels.

Targets

ABCC8, ACE, ADRB3, AGT, AKT2, AQP2, AVPR2, CD28, CTLA4, ENPP1, FBP1, FOXC2, FOXP3, GCG, GCGR, GCK, HNF1B, HNF4A, IDE, IFNG, IKBKB, IL10, IL12B, INS, INSR, IRS1, IRS2, NEUROD1, NOS3, PDX1, PLAGL1, PPARA, PPARG, PPARGC1B, PTPN1, PTPN22, PTPRN, RETN, RRAD, SLC2A2, SLC2A4, TNF, UCP1, WFS1

Controls

18S, GAPDH, GUSB, HPRT1

Pathway Information

Diabetes mellitus is a chronic disease characterized by high blood glucose levels. Long-term medical attention is usually required to limit the development of and management of complications resulting from the disease. The pancreatic beta-cell and its sec ...
View More...


Supported Applied Biosystems Instruments

7500 Fast Real-Time PCR System , StepOnePlus™ System , ViiA™ 7 System , 7900HT Real-Time PCR System , QuantStudio™ 12K Flex System , QuantStudio™ 7 Flex System , QuantStudio™ 6 Flex System , QuantStudio™ 5 System , QuantStudio™ 3 System

View Full Details