Panel Description

The TaqMan® Array Human Cyclins And Cell Cycle Regulation contains 44 assays to cyclins and cell cycle regulation associated genes and 4 assays to candidate endogenous control genes.

Targets

ATM, ATR, CCNA1, CCNA2, CCNB1, CCNB2, CCND1, CCND2, CCND3, CCNE1, CCNE2, CCNH, CDC2, CDC25A, CDK2, CDK4, CDK6, CDK7, CDKN1A, CDKN1B, CDKN2A, CDKN2B, CDKN2C, CDKN2D, E2F1, E2F2, E2F3, E2F4, GSK3B, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC9, PPP2CA, RAF1, RB1, TGFB1, TGFB2, TGFB3, TP53

Controls

18S, GAPDH, GUSB, HPRT1

Pathway Information

Progress in the eukaryotic cell cycle is driven by oscillations in the activities of CDKs (Cyclin-Dependent Kinases). CDK activity is controlled by periodic synthesis and degradation of positive regulatory subunits, Cyclins, as well as by fluctuations in ...
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Supported Applied Biosystems Instruments

7500 Fast Real-Time PCR System , StepOnePlus™ System , ViiA™ 7 System , 7900HT Real-Time PCR System , QuantStudio™ 12K Flex System , QuantStudio™ 7 Flex System , QuantStudio™ 6 Flex System , QuantStudio™ 5 System , QuantStudio™ 3 System

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