Panel Description

The Fibrosis array includes genes involved in occurance of dysregulated tissue remodeling, where extracellular matrix (ECM) deposition occurs during the repair and healing of wounds. Included in the array along with fibrosis related genes are those that encode ECM remodeling enzymes, TGFβ signaling molecules and inflammatory cytokines.

Targets(Suggested)

ACTA2, AGT, AKT1, BCL2, BMP7, CAV1, CCL11, CCL2, CCL3, CCR2, CEBPB, COL1A2, COL3A1, CTGF, CXCR4, DCN, EDN1, EGF, ENG, FASLG, GREM1, HGF, IFNG, IL10, IL13, IL13RA2, IL1A, IL1B, IL4, IL5, ILK, INHBE, ITGA1, ITGA2, ITGA3, ITGAV, ITGB1, ITGB3, ITGB5, ITGB6, ITGB8, JUN, LOX, LTBP1, MMP1, MMP13, MMP14, MMP2, MMP3, MMP8, MMP9...
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Controls

18s rRNA, ACTB, B2M, GAPDH, GUSB, HMBS, HPRT1, IPO8, PGK1, RPLP0, TBP, TFRC

Targets(Additonal)

UBC

Supported Applied Biosystems Instruments

7500 Fast Real-Time PCR System , StepOnePlus™ System , ViiA™ 7 System , 7900HT Real-Time PCR System , QuantStudio™ 12K Flex System , QuantStudio™ 7 Flex System , QuantStudio™ 6 Flex System , QuantStudio™ 5 System , QuantStudio™ 3 System