Product Details

Primer Sequences

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Primer Chromosome Location

Chr.19: 2190847-2191343 on Build GRCh38 View in UCSC browser

Format

Each primer will be delivered in a single tube, dried-down

Quick Reference Guide

Primer Designer^™ Tool Quick Reference

Ampliseq ID's

Gene Details

Gene Symbol

DOT1L

Entrez Gene ID

84444

Gene Name

DOT1 like histone lysine methyltransferase

Gene Aliases

DOT1, KMT4

UniGene

Hs.713641

Gene Chromosome Location

Chr.19: 2163963-2232578 on Build GRCh38

Transcripts

NM_032482.2 XM_005259659.3 XM_005259660.3 XM_011528359.2 XM_011528360.1 XM_017027366.1

Cosmic Detail

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Cosmic ID	Mutation	AA	Transcript Location
6891608	c.439A>G	p.M147V	Chr.19: 2191186-2191186 on Build GRCh38
6964254	c.290A>G	p.K97R	Chr.19: 2191037-2191037 on Build GRCh38
3764719	c.355G>T	p.V119L	Chr.19: 2191102-2191102 on Build GRCh38
1148141	c.399C>G	p.P133P	Chr.19: 2191146-2191146 on Build GRCh38
6945384	c.284C>T	p.P95L	Chr.19: 2191031-2191031 on Build GRCh38
3822500	c.345C>A	p.Y115*	Chr.19: 2191092-2191092 on Build GRCh38
4991278	c.396C>T	p.S132S	Chr.19: 2191143-2191143 on Build GRCh38
5855240	c.453delC	p.K152fs*2	Chr.19: 2191200-2191200 on Build GRCh38
6918703	c.383A>T	p.Y128F	Chr.19: 2191130-2191130 on Build GRCh38
3989874	c.365C>G	p.P122R	Chr.19: 2191112-2191112 on Build GRCh38
6929488	c.481G>T	p.D161Y	Chr.19: 2191228-2191228 on Build GRCh38
6648751	c.409G>A	p.G137R	Chr.19: 2191156-2191156 on Build GRCh38
6921669	c.424G>T	p.D142Y	Chr.19: 2191171-2191171 on Build GRCh38
4679190	c.466G>A	p.D156N	Chr.19: 2191213-2191213 on Build GRCh38
4679191	c.466G>A	p.D156N	Chr.19: 2191213-2191213 on Build GRCh38
4991279	c.396C>T	p.S132S	Chr.19: 2191143-2191143 on Build GRCh38
4076202	c.331C>A	p.L111M	Chr.19: 2191078-2191078 on Build GRCh38
6975837	c.469G>A	p.D157N	Chr.19: 2191216-2191216 on Build GRCh38
1196307	c.493G>T	p.G165C	Chr.19: 2191240-2191240 on Build GRCh38
710860	c.399C>G	p.P133P	Chr.19: 2191146-2191146 on Build GRCh38
6866892	c.465C>T	p.D155D	Chr.19: 2191212-2191212 on Build GRCh38
6929487	c.481G>T	p.D161Y	Chr.19: 2191228-2191228 on Build GRCh38
6924740	c.322C>T	p.R108C	Chr.19: 2191069-2191069 on Build GRCh38
3989875	c.365C>G	p.P122R	Chr.19: 2191112-2191112 on Build GRCh38
6891607	c.439A>G	p.M147V	Chr.19: 2191186-2191186 on Build GRCh38
4076203	c.331C>A	p.L111M	Chr.19: 2191078-2191078 on Build GRCh38
3103120	c.299C>T	p.T100M	Chr.19: 2191046-2191046 on Build GRCh38
6648752	c.409G>A	p.G137R	Chr.19: 2191156-2191156 on Build GRCh38
6975838	c.469G>A	p.D157N	Chr.19: 2191216-2191216 on Build GRCh38
6918702	c.383A>T	p.Y128F	Chr.19: 2191130-2191130 on Build GRCh38
6921668	c.424G>T	p.D142Y	Chr.19: 2191171-2191171 on Build GRCh38
3103121	c.299C>T	p.T100M	Chr.19: 2191046-2191046 on Build GRCh38
1304290	c.343T>A	p.Y115N	Chr.19: 2191090-2191090 on Build GRCh38
5530151	c.360C>T	p.T120T	Chr.19: 2191107-2191107 on Build GRCh38
6945383	c.284C>T	p.P95L	Chr.19: 2191031-2191031 on Build GRCh38
5583461	c.365C>T	p.P122L	Chr.19: 2191112-2191112 on Build GRCh38
4496330	c.472C>T	p.L158L	Chr.19: 2191219-2191219 on Build GRCh38
6538977	c.375C>G	p.L125L	Chr.19: 2191122-2191122 on Build GRCh38
6866893	c.465C>T	p.D155D	Chr.19: 2191212-2191212 on Build GRCh38
6084055	c.493+1G>T	p.?	Chr.19: 2191241-2191241 on Build GRCh38
6915021	c.466G>T	p.D156Y	Chr.19: 2191213-2191213 on Build GRCh38
6956427	c.395delC	p.E134fs*14	Chr.19: 2191142-2191142 on Build GRCh38
6924739	c.322C>T	p.R108C	Chr.19: 2191069-2191069 on Build GRCh38
4076199	c.271G>T	p.G91C	Chr.19: 2191018-2191018 on Build GRCh38
1196306	c.493G>T	p.G165C	Chr.19: 2191240-2191240 on Build GRCh38
6648719	c.300G>A	p.T100T	Chr.19: 2191047-2191047 on Build GRCh38
6328878	c.319C>A	p.L107M	Chr.19: 2191066-2191066 on Build GRCh38
6947069	c.269A>C	p.K90T	Chr.19: 2191016-2191016 on Build GRCh38
4076204	c.353C>T	p.S118L	Chr.19: 2191100-2191100 on Build GRCh38
6945707	c.412G>T	p.E138*	Chr.19: 2191159-2191159 on Build GRCh38
6538978	c.375C>G	p.L125L	Chr.19: 2191122-2191122 on Build GRCh38
6956426	c.395delC	p.E134fs*14	Chr.19: 2191142-2191142 on Build GRCh38
6915020	c.466G>T	p.D156Y	Chr.19: 2191213-2191213 on Build GRCh38
3764718	c.355G>T	p.V119L	Chr.19: 2191102-2191102 on Build GRCh38
5017269	c.359_364delCCGACC	p.D121_P122delDP	Chr.19: 2191106-2191111 on Build GRCh38
5530150	c.360C>T	p.T120T	Chr.19: 2191107-2191107 on Build GRCh38
1304289	c.343T>A	p.Y115N	Chr.19: 2191090-2191090 on Build GRCh38
4412759	c.440T>A	p.M147K	Chr.19: 2191187-2191187 on Build GRCh38
6964255	c.290A>G	p.K97R	Chr.19: 2191037-2191037 on Build GRCh38
5017268	c.359_364delCCGACC	p.D121_P122delDP	Chr.19: 2191106-2191111 on Build GRCh38
6328879	c.319C>A	p.L107M	Chr.19: 2191066-2191066 on Build GRCh38
5583460	c.365C>T	p.P122L	Chr.19: 2191112-2191112 on Build GRCh38
4076200	c.271G>T	p.G91C	Chr.19: 2191018-2191018 on Build GRCh38
6084054	c.493+1G>T	p.?	Chr.19: 2191241-2191241 on Build GRCh38
6648718	c.300G>A	p.T100T	Chr.19: 2191047-2191047 on Build GRCh38
4412758	c.440T>A	p.M147K	Chr.19: 2191187-2191187 on Build GRCh38
6947068	c.269A>C	p.K90T	Chr.19: 2191016-2191016 on Build GRCh38
3822499	c.345C>A	p.Y115*	Chr.19: 2191092-2191092 on Build GRCh38
6945706	c.412G>T	p.E138*	Chr.19: 2191159-2191159 on Build GRCh38
4076205	c.353C>T	p.S118L	Chr.19: 2191100-2191100 on Build GRCh38
5855239	c.453delC	p.K152fs*2	Chr.19: 2191200-2191200 on Build GRCh38
4496331	c.472C>T	p.L158L	Chr.19: 2191219-2191219 on Build GRCh38

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SNP Detail

SNP ID	Chromosome Location
rs773066675	Chr.19: 2191107-2191107 on Build GRCh38
rs374871901	Chr.19: 2190974-2190974 on Build GRCh38
rs545519594	Chr.19: 2190914-2190914 on Build GRCh38
rs772598468	Chr.19: 2191254-2191254 on Build GRCh38
rs778167150	Chr.19: 2191210-2191210 on Build GRCh38
rs767545375	Chr.19: 2191273-2191273 on Build GRCh38
rs919523268	Chr.19: 2190932-2190932 on Build GRCh38
rs371826966	Chr.19: 2191262-2191262 on Build GRCh38
rs756501559	Chr.19: 2191209-2191209 on Build GRCh38
rs762979072	Chr.19: 2191029-2191029 on Build GRCh38
rs114452263	Chr.19: 2190920-2190920 on Build GRCh38
rs766429376	Chr.19: 2191113-2191113 on Build GRCh38
rs62120553	Chr.19: 2191263-2191263 on Build GRCh38
rs369416791	Chr.19: 2191077-2191077 on Build GRCh38
rs750330281	Chr.19: 2191026-2191026 on Build GRCh38
rs756411550	Chr.19: 2191053-2191053 on Build GRCh38
rs961170094	Chr.19: 2190913-2190913 on Build GRCh38
rs775727279	Chr.19: 2191284-2191284 on Build GRCh38
rs939872664	Chr.19: 2191312-2191312 on Build GRCh38
rs578103392	Chr.19: 2191315-2191315 on Build GRCh38
rs35301355	Chr.19: 2190949-2190951 on Build GRCh38
rs757223925	Chr.19: 2190919-2190919 on Build GRCh38
rs542716517	Chr.19: 2191167-2191167 on Build GRCh38
rs774216699	Chr.19: 2191260-2191260 on Build GRCh38
rs201065643	Chr.19: 2191146-2191146 on Build GRCh38
rs376930276	Chr.19: 2191292-2191292 on Build GRCh38
rs34470909	Chr.19: 2191128-2191128 on Build GRCh38
rs370269437	Chr.19: 2191131-2191131 on Build GRCh38
rs377129936	Chr.19: 2191289-2191289 on Build GRCh38
rs955448796	Chr.19: 2191184-2191184 on Build GRCh38
rs905499758	Chr.19: 2191306-2191306 on Build GRCh38
rs755180991	Chr.19: 2191044-2191044 on Build GRCh38
rs530771095	Chr.19: 2190923-2190923 on Build GRCh38
rs761000170	Chr.19: 2190950-2190952 on Build GRCh38
rs984751311	Chr.19: 2191140-2191140 on Build GRCh38
rs377118891	Chr.19: 2191101-2191101 on Build GRCh38
rs748714168	Chr.19: 2190984-2190984 on Build GRCh38
rs757313197	Chr.19: 2191069-2191069 on Build GRCh38
rs749760864	Chr.19: 2191059-2191059 on Build GRCh38
rs1004128160	Chr.19: 2191065-2191065 on Build GRCh38
rs200726568	Chr.19: 2191239-2191239 on Build GRCh38
rs753064843	Chr.19: 2191047-2191047 on Build GRCh38
rs113111011	Chr.19: 2191288-2191288 on Build GRCh38
rs186656087	Chr.19: 2191249-2191249 on Build GRCh38
rs914492897	Chr.19: 2191256-2191256 on Build GRCh38
rs759545923	Chr.19: 2191155-2191155 on Build GRCh38
rs745382072	Chr.19: 2190999-2190999 on Build GRCh38
rs563794467	Chr.19: 2191170-2191170 on Build GRCh38
rs777928562	Chr.19: 2190872-2190872 on Build GRCh38
rs915624512	Chr.19: 2191279-2191279 on Build GRCh38
rs765266134	Chr.19: 2191023-2191023 on Build GRCh38
rs751781537	Chr.19: 2191041-2191041 on Build GRCh38
rs762929142	Chr.19: 2191110-2191110 on Build GRCh38
rs113478946	Chr.19: 2190894-2190894 on Build GRCh38
rs781027157	Chr.19: 2191250-2191250 on Build GRCh38
rs377682303	Chr.19: 2191008-2191008 on Build GRCh38
rs962740409	Chr.19: 2190875-2190875 on Build GRCh38
rs1028383704	Chr.19: 2191182-2191182 on Build GRCh38
rs755379104	Chr.19: 2190969-2190969 on Build GRCh38
rs886983194	Chr.19: 2191048-2191048 on Build GRCh38
rs11879054	Chr.19: 2191212-2191212 on Build GRCh38
rs541446006	Chr.19: 2190885-2190885 on Build GRCh38
rs553428044	Chr.19: 2190892-2190892 on Build GRCh38
rs778164791	Chr.19: 2191057-2191057 on Build GRCh38
rs374436091	Chr.19: 2191004-2191004 on Build GRCh38
rs781606489	Chr.19: 2191046-2191046 on Build GRCh38
rs202184030	Chr.19: 2191061-2191061 on Build GRCh38
rs905530918	Chr.19: 2191050-2191050 on Build GRCh38
rs770281883	Chr.19: 2190990-2190990 on Build GRCh38
rs760343293	Chr.19: 2191007-2191007 on Build GRCh38
rs868594663	Chr.19: 2190942-2190942 on Build GRCh38
rs746518040	Chr.19: 2191248-2191248 on Build GRCh38
rs746714270	Chr.19: 2191070-2191070 on Build GRCh38
rs570920920	Chr.19: 2191034-2191034 on Build GRCh38
rs752866665	Chr.19: 2191176-2191176 on Build GRCh38
rs1028435724	Chr.19: 2190898-2190898 on Build GRCh38
rs146911119	Chr.19: 2191080-2191080 on Build GRCh38
rs935695285	Chr.19: 2190986-2190986 on Build GRCh38
rs966988631	Chr.19: 2190956-2190956 on Build GRCh38
rs987001924	Chr.19: 2190926-2190926 on Build GRCh38
rs542539784	Chr.19: 2190928-2190928 on Build GRCh38
rs773703430	Chr.19: 2190996-2190996 on Build GRCh38
rs773049220	Chr.19: 2191253-2191253 on Build GRCh38
rs943495021	Chr.19: 2190970-2190970 on Build GRCh38
rs1035156898	Chr.19: 2190897-2190897 on Build GRCh38
rs374088546	Chr.19: 2191003-2191003 on Build GRCh38
rs371155512	Chr.19: 2191215-2191215 on Build GRCh38
rs761904286	Chr.19: 2191020-2191020 on Build GRCh38
rs374013420	Chr.19: 2191083-2191083 on Build GRCh38
rs796978361	Chr.19: 2190955-2190957 on Build GRCh38
rs561263871	Chr.19: 2190952-2190952 on Build GRCh38

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