gRNA Design Details

Target DNA Sequence
GCGGTAGGGAATCACAAAGT
PAM Sequence
GGG
Target locus
Chr.21: 26089950 - 26089972 on GRCh38
Strand
Forward
Application
Gene Knockout
Score: 89.08/100

Rank:
scoring gRNA

Targeted Gene

Gene Symbol
APP
Entrez Gene ID
351
Gene Name
amyloid beta precursor protein
Gene Aliases
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Chromosome Location
Chr.21: 25880550 - 26171128 on GRCh38
UniGene ID
Hs.434980
Species
Human

Targeted Isoforms Translated Protein Targeted Exon(s)
RefSeq NM_000484.3 NP_000475.1 3
NM_001136016.3 NP_001129488.1 3
NM_001136129.2 NP_001129601.1 2
NM_001136130.2 NP_001129602.1 2
NM_001136131.2 NP_001129603.1 3
NM_001204301.1 NP_001191230.1 3
NM_001204302.1 NP_001191231.1 3
NM_001204303.1 NP_001191232.1 3
NM_201413.2 NP_958816.1 3
NM_201414.2 NP_958817.1 3