gRNA Design Details

Target DNA Sequence
GCCACAATATGACATTACGA
PAM Sequence
TGG
Target locus
Chr.6: 117404361 - 117404383 on GRCh38
Strand
Reverse
Application
Gene Knockout
Score: 91.13/100

Rank:
scoring gRNA

Targeted Gene

Gene Symbol
ROS1
Entrez Gene ID
6098
Gene Name
ROS proto-oncogene 1, receptor tyrosine kinase
Gene Aliases
MCF3, ROS, c-ros-1
Chromosome Location
Chr.6: 117287918 - 117426065 on GRCh38
UniGene ID
Hs.1041
Species
Human

Targeted Isoforms Translated Protein Targeted Exon(s)
RefSeq NM_002944.2 NP_002935.2 5
XM_006715548.3 XP_006715611.1 6
XM_011536049.2 XP_011534351.1 6
XM_011536050.2 XP_011534352.1 6
XM_011536051.2 XP_011534353.1 5
XM_011536052.2 XP_011534354.1 6
XM_011536053.2 XP_011534355.1 6
XM_011536054.2 XP_011534356.1 6
XM_011536055.2 XP_011534357.1 6
XM_011536056.2 XP_011534358.1 6
XM_011536057.2 XP_011534359.1 6
XM_011536058.2 XP_011534360.1 6
XM_017011172.1 XP_016866661.1 5
XM_017011173.1 XP_016866662.1 5