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Your search for "dusp3" returned 34 TaqMan® Gene Expression Assays
dual specificity phosphatase 3
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq, Jul 2008]
|Protocol||Protocol: TaqMan® Gene Expression Assays||PDF, Unknown KB|
|App Note||Application Note: TaqMan® Gene Expression Assays Endogenous Controls||PDF, Unknown KB|
|QRC||QRC: TaqMan® Gene Expression Assays||PDF, Unknown KB|
|White Paper||Design Process for Gene Expression Assays||PDF, Unknown KB|
|White Paper||Gene Expression Assay Performance Guarantee||PDF, Unknown KB|
|White Paper||TaqMan® Assays shipped at ambient temperature retain their quality and stability||PDF, Unknown KB|
|Brochure||Understanding Your Shipment||PDF, Unknown KB|
|White Paper||Product Stability Study||PDF, Unknown KB|
|Spreadsheet||Pathogen Assay Information||XLSX, Unknown KB|
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