Your search for "itm2b" returned 103 TaqMan® SNP Genotyping Assays
integral membrane protein 2B
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
ABRI, AI256040, BRI, BRI2, BRICD2B, D14SEL6, E25B, E25BMM, E3-16, FBD, IMBRI2, ITM2B, RDGCA
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