Your search for "nfx1" returned 462 TaqMan® SNP Genotyping Assays
nuclear transcription factor, X-box binding 1
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008]
1300017N15RIK, 3000003M19RIK, NFX.1, NFX1, NFX2, TEG-42, TEX42
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