Your search for "psmc5" returned 46 TaqMan® SNP Genotyping Assays
proteasome 26S subunit, ATPase 5
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
MSUG1, P45, P45/SUG, PSMC5, S8, SUG-1, SUG1, TBP10, TRIP1
(Human) P62195, (Human) A8K3Z3, (Human) A8K763, (Human) O35051, (Human) O43208, (Human) P47210, (Human) P52915, (Human) P52916, (Mouse) P62196, (Mouse) O35051, (Mouse) P47210, (Mouse) P52915, (Mouse) P52916, (Mouse) Q3UL51, (Mouse) Q9CWN5, (Rat) P62198, (Rat) O35051, (Rat) P47210, (Rat) P52915, (Rat) P52916
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