Your search for "ptpn11" returned 119 TaqMan® SNP Genotyping Assays
protein tyrosine phosphatase, non-receptor type 11
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
2700084A17RIK, AW536184, BPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP1D, PTP2C, PTPN11, SAP-2, SH-PTP2, SH-PTP3, SHP-2, SHP2, SYP
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