Your search for "rrm2b" returned 154 TaqMan® SNP Genotyping Assays
ribonucleotide reductase regulatory TP53 inducible subunit M2B
This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
MTDPS8A, MTDPS8B, P53R2, RRM2B
Please enter the information below and press OK to send your cart to Core Services for purchase.