Your search for "sptlc3" returned 641 TaqMan® SNP Genotyping Assays
serine palmitoyltransferase long chain base subunit 3
The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT; EC 188.8.131.52), which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al., 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3), depending on the tissue in which biosynthesis occurs (Hornemann et al., 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit, SSSPTA (MIM 613540) and SSSPTB (MIM 610412), that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]
C130053K05RIK, C20ORF38, DJ718P11, DJ718P11.1, HLCB2B, LCB2B, LCB3, RGD1310030, SPT3, SPTLC2L, SPTLC3
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