Your search for "tnfrsf1b" returned 242 TaqMan® SNP Genotyping Assays
TNF receptor superfamily member 1B
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
CD120B, P75, P75TNFR, TBPII, TNF-ALPHAR2, TNF-R-II, TNF-R2, TNF-R75, TNFALPHA-R2, TNFBR, TNFR-1, TNFR1B, TNFR2, TNFR80, TNFRII, TNFRSF1B
Please enter the information below and press OK to send your cart to Core Services for purchase.