Your search for "zak" returned 578 TaqMan® SNP Genotyping Assays
sterile alpha motif and leucine zipper containing kinase AZK
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
AV006891, AZK, B230120H23RIK, MLK7, MLKLAK, MLT, MLTK, MLTKALPHA, MLTKBETA, MRK, PK, RGD1561394, SFMMP, ZAK
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