Your search for "PRDM9" returned 31 siRNAs
PR domain 9
The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described. [provided by RefSeq, Jul 2015]
BC012016, DSBC1, G1-419-29, MEISETZ, MSBP3, PFM6, PRDM7, PRDM9, RCR1, REPRO7, ZNF899
(Human) Q9NQV7, (Human) B4DX22, (Human) Q27Q50, (Rat) P0C6Y7