Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-803 detects endogenous Tpit from mouse AtT-20 cell lysates.
PA1-803 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~48 kDa protein representing Tpit from AtT-20 cells.
PA1-803 immunizing protein, bacterially produced, corresponds to the mouse C-terminal region of Tpit.
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: T-box factor, pituitary; T-box protein 19; T-box transcription factor TBX19
Gene Aliases: Tbx19; Tpit
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support