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Immunogen sequence: MDDKAFTKEL DQWVEQLNEC KQLNENQVRT LCEKAKEILT KESNVQEVRC PVTVCGDVHG QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER ITILRGNHES RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL SPSIDTLDHI RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH ANGLTLVSRA HQLVMEGYNW CHDRNVVTIF SAPNYCYRCG NQAAIMELDD TLKYSFLQFD PAPRRGEPHV TRRTPDYFL; Positive Samples: LO2, 293T, Mouse brain, Mouse lung, Mouse spleen, Rat liver; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, spindle pole
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.
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Protein Aliases: PP2A beta; PP2A-beta; PPP2bc; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2A catalytic alpha subunit; protein phosphatase 2A catalytic subunit, beta isoform; protein phosphatase 2a, catalytic subunit, beta isoform; protein phosphatase type 2A catalytic subunit; protein phosphatase-2A-beta; serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; testicular tissue protein Li 146
Gene Aliases: AI115466; D8Ertd766e; Pp2a2; PP2Abeta; PP2Ac; PP2CB; PPP2CB
UniProt ID: (Human) P62714, (Rat) P62716, (Mouse) P62715
Entrez Gene ID: (Human) 5516, (Rat) 24673, (Mouse) 19053
Molecular Function: protein phosphatase
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