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LOADING
Gene Symbol:
PIK3CA
Entrez Gene ID
5290
Gene Name:
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Gene Aliases
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, PI3K-alpha, p110-alpha
Gene Chromosome Location
Chr.3: on Build GRCh38
UniGene
Hs.553498
Species:
Human
Primer Chromosome Location
Chr.3: 179201303-179201435 on Build GRCh38
View in UCSC browser
Amplicon Length
133
Primer Sequences
Log in to view
Ampliseq ID's
Primer ID
Hs00522659_CE
Primer 5'-tail Option
Non-tailed
M13-tailed
Purification
Desalted
HPLC
Primer Pair /FWD/REV
Pair
Forward
Reverse
Synthesis Scale
25 nmol
Availability
Made To Order
Catalog #'s
A15629,A15630
Price
Add To Cart
Genomic Map
Assay Details
More Information
Genomic Map
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Assay Details
Gene Information
PIK3CA
Accession
Protein
COSMIC ID
Mutation
AA
RefSeq
NM_006218.3
NP_006209.2
3695924
c.670G>T
p.A224S
6189010
c.584G>A
p.W195*
6475749
c.638A>C
p.H213P
6964034
c.596C>G
p.S199C
5398692
c.678G>C
p.R226S
6925490
c.688C>T
p.R230*
86047
c.665C>T
p.A222V
6475771
c.655C>T
p.Q219*
6475672
c.633C>A
p.I211I
6932200
c.703T>A
p.S235T
5609833
c.704C>T
p.S235L
7344892
c.612G>T
p.K204N
6475621
c.688C>A
p.R230R
6475663
c.577G>A
p.V193M
6973969
c.635A>G
p.N212S
6475751
c.602A>G
p.N201S
4398724
c.705C>T
p.S235S
6475686
c.579G>A
p.V193V
6475623
c.707C>A
p.S236Y
4763696
c.643T>G
p.C215G
729827
c.627G>A
p.L209L
XM_006713658.3
XP_006713721.1
-
-
-
XM_011512894.2
XP_011511196.1
-
-
-
GenBank
AB210020.1
-
-
-
AK292940.1
-
-
-
AK297203.1
-
-
-
AK302608.1
-
-
-
BC113601.1
-
-
-
BC113603.1
-
-
-
U79143.1
AAB39753.1
-
-
-
Z29090.1
CAA82333.1
-
-
-
Phenotype
MIM: 171834
Literature Links:
PIK3CA
PubMed Links
SNP ID
rs200131834
rs751662352
rs943131817
rs587777792
rs910287504
rs372610277
Submission count
NA
Allele Nomenclature
Chromosome Location
Chr.3: 179201341-179201341 on Build GRCh38
Allele Frequency
1000Genome
Applied Biosystems
®
HapMap
Global - Not Available
Caucasian - Not Available
CEPH (CEU) - Not Available
EAS - Not Available
African American - Not Available
YRI (Yoruba) - Not Available
SAS - Not Available
Chinese - Not Available
CHB (Han Chinese) - Not Available
AFR - Not Available
Japanese - Not Available
JPT (Japanese) - Not Available
EUR - Not Available
AMR - Not Available
Submission count
NA
Allele Nomenclature
Chromosome Location
Chr.3: 179201362-179201362 on Build GRCh38
Allele Frequency
1000Genome
Applied Biosystems
®
HapMap
Global - Not Available
Caucasian - Not Available
CEPH (CEU) - Not Available
EAS - Not Available
African American - Not Available
YRI (Yoruba) - Not Available
SAS - Not Available
Chinese - Not Available
CHB (Han Chinese) - Not Available
AFR - Not Available
Japanese - Not Available
JPT (Japanese) - Not Available
EUR - Not Available
AMR - Not Available
Submission count
NA
Allele Nomenclature
Chromosome Location
Chr.3: 179201395-179201395 on Build GRCh38
Allele Frequency
1000Genome
Applied Biosystems
®
HapMap
Global - Not Available
Caucasian - Not Available
CEPH (CEU) - Not Available
EAS - Not Available
African American - Not Available
YRI (Yoruba) - Not Available
SAS - Not Available
Chinese - Not Available
CHB (Han Chinese) - Not Available
AFR - Not Available
Japanese - Not Available
JPT (Japanese) - Not Available
EUR - Not Available
AMR - Not Available
Submission count
NA
Allele Nomenclature
Chromosome Location
Chr.3: 179201379-179201379 on Build GRCh38
Allele Frequency
1000Genome
Applied Biosystems
®
HapMap
Global - Not Available
Caucasian - Not Available
CEPH (CEU) - Not Available
EAS - Not Available
African American - Not Available
YRI (Yoruba) - Not Available
SAS - Not Available
Chinese - Not Available
CHB (Han Chinese) - Not Available
AFR - Not Available
Japanese - Not Available
JPT (Japanese) - Not Available
EUR - Not Available
AMR - Not Available
Submission count
NA
Allele Nomenclature
Chromosome Location
Chr.3: 179201373-179201373 on Build GRCh38
Allele Frequency
1000Genome
Applied Biosystems
®
HapMap
Global - Not Available
Caucasian - Not Available
CEPH (CEU) - Not Available
EAS - Not Available
African American - Not Available
YRI (Yoruba) - Not Available
SAS - Not Available
Chinese - Not Available
CHB (Han Chinese) - Not Available
AFR - Not Available
Japanese - Not Available
JPT (Japanese) - Not Available
EUR - Not Available
AMR - Not Available
Submission count
NA
Allele Nomenclature
Chromosome Location
Chr.3: 179201350-179201350 on Build GRCh38
Allele Frequency
1000Genome
Applied Biosystems
®
HapMap
Global - Not Available
Caucasian - Not Available
CEPH (CEU) - Not Available
EAS - Not Available
African American - Not Available
YRI (Yoruba) - Not Available
SAS - Not Available
Chinese - Not Available
CHB (Han Chinese) - Not Available
AFR - Not Available
Japanese - Not Available
JPT (Japanese) - Not Available
EUR - Not Available
AMR - Not Available
Back To Top
More Information
Set Membership:
Less than 200 bp
Panther Classification:
Molecular Function -
kinase
Gene Ontology Categories:
Function(s)
Process(es)
angiogenesis
liver development
vasculature development
glucose metabolic process
protein phosphorylation
phosphatidylinositol biosynthetic process
epidermal growth factor receptor signaling pathway
regulation of gene expression
regulation of phosphatidylinositol 3-kinase signaling
platelet activation
T cell costimulation
activation of protein kinase activity
positive regulation of peptidyl-serine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
insulin receptor signaling pathway via phosphatidylinositol 3-kinase
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
ERBB2 signaling pathway
regulation of multicellular organism growth
regulation of cellular respiration
protein kinase B signaling
negative regulation of neuron apoptotic process
endothelial cell migration
hypomethylation of CpG island
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
leukocyte migration
cardiac muscle contraction
adipose tissue development
cellular response to glucose stimulus
energy homeostasis
mitophagy in response to mitochondrial depolarization
negative regulation of fibroblast apoptotic process
regulation of genetic imprinting
negative regulation of anoikis
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
1-phosphatidylinositol-3-kinase activity
protein kinase activator activity
phosphatidylinositol 3-kinase activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Format:
Each primer will be delivered in a single tube, dried-down
Quick Reference Guide
Primer Designer
™
Tool Quick Reference
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Host server : magellan-search-65b4bdbffd-9jqhn:80/10.239.160.220:80.
git-commit: b16971a8df2afcd8df684aafbc9bf1e9f45e42d4
git-url: git@github.com:thermofisher/magellan-core.git
git-branch: origin/release/2.6.0-2024.04.15-1.0