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          System Message

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          LOADING ...
          See other TLR4 EBGEX Assays ›
          Gene Symbol:
          TLR4
          Gene Name:
          toll like receptor 4
          Gene Aliases:
          ARMD10, CD284, TLR-4, TOLL
          Chromosome Location:
          Chr.9: 117704403 - 117724735 on Build GRCh38
          UniGene ID:
          Hs.174312
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Type:
          6
          Detection Label:
          Alexa Fluor 647
          ProductType:
          ViewRNA Cell Plus Probe Set
          Assay ID VA6-17278-VCP
          Size
          Availability Made To Order
          Catalog # VX-06
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: TLR4
          Interrogated Sequence Translated Protein IMAGE Clone ID
          RefSeq NM_003266.4 NP_003257.1
          NM_138554.5 NP_612564.1
          NM_138557.3 NP_612567.1
          GenBank mRNA AA598398.1 -
          AB445638.1 -
          AK226155.1 -
          AK290053.1 -
          AK293068.1 -
          AK303730.1 -
          AL710219.1 -
          BC025294.1 -
          BC117422.1 -
          BC143841.1 -
          BG622357.1 -
          DA126770.1 -
          DA187988.1 -
          DA218006.1 -
          U69193.2 -
          U88880.1 -
          U93091.1 -

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          activation of innate immune response
          toll-like receptor signaling pathway
          wound healing involved in inflammatory response
          B cell proliferation involved in immune response
          immune system process
          nitric oxide production involved in inflammatory response
          regulation of dendritic cell cytokine production
          MyD88-dependent toll-like receptor signaling pathway
          nitric oxide biosynthetic process
          phagocytosis
          defense response
          inflammatory response
          immune response
          signal transduction
          I-kappaB kinase/NF-kappaB signaling
          JNK cascade
          response to bacterium
          gene expression
          positive regulation of platelet activation
          positive regulation of gene expression
          astrocyte development
          microglia differentiation
          positive regulation of smooth muscle cell migration
          detection of fungus
          neurogenesis
          signal transduction involved in regulation of gene expression
          positive regulation of B cell proliferation
          lipopolysaccharide-mediated signaling pathway
          response to lipopolysaccharide
          detection of lipopolysaccharide
          regulation of tumor necrosis factor production
          negative regulation of interferon-gamma production
          negative regulation of interleukin-17 production
          negative regulation of interleukin-23 production
          negative regulation of interleukin-6 production
          negative regulation of tumor necrosis factor production
          positive regulation of chemokine production
          positive regulation of interferon-alpha production
          positive regulation of interferon-beta production
          positive regulation of interferon-gamma production
          positive regulation of interleukin-1 beta production
          positive regulation of interleukin-1 production
          positive regulation of interleukin-10 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-6 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          positive regulation of stress-activated MAPK cascade
          toll-like receptor 4 signaling pathway
          regulation of toll-like receptor 4 signaling pathway
          TRIF-dependent toll-like receptor signaling pathway
          cellular response to platelet-derived growth factor stimulus
          T-helper 1 type immune response
          B cell proliferation
          macrophage activation
          defense response to bacterium
          positive regulation of macrophage activation
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          innate immune response
          leukocyte activation
          MHC class II biosynthetic process
          positive regulation of MHC class II biosynthetic process
          positive regulation of nitric oxide biosynthetic process
          negative regulation of osteoclast differentiation
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          lymphocyte proliferation
          positive regulation of smooth muscle cell proliferation
          positive regulation of lymphocyte proliferation
          regulation of inflammatory response
          positive regulation of inflammatory response
          defense response to Gram-negative bacterium
          positive regulation of NF-kappaB transcription factor activity
          NK T cell activation
          stress-activated MAPK cascade
          detection of stimulus
          intestinal epithelial structure maintenance
          positive regulation of macrophage cytokine production
          ERK1 and ERK2 cascade
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of ERK1 and ERK2 cascade
          nucleotide-binding oligomerization domain containing 1 signaling pathway
          positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
          nucleotide-binding oligomerization domain containing 2 signaling pathway
          positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
          cellular response to lipopolysaccharide
          cellular response to lipoteichoic acid
          cellular response to mechanical stimulus
          cellular response to interferon-gamma
          negative regulation of cold-induced thermogenesis
          cellular response to oxidised low-density lipoprotein particle stimulus
          negative regulation of cytokine production involved in inflammatory response
          positive regulation of cytokine production involved in inflammatory response
          positive regulation of NLRP3 inflammasome complex assembly
          positive regulation of reactive oxygen species biosynthetic process
          positive regulation of cellular response to macrophage colony-stimulating factor stimulus
          positive regulation of matrix metallopeptidase secretion
          cellular response to beta-amyloid
          positive regulation of chemokine (C-X-C motif) ligand 2 production
          positive regulation of extrinsic apoptotic signaling pathway
          lipopolysaccharide binding
          beta-amyloid binding
          lipopolysaccharide receptor activity
          transmembrane signaling receptor activity
          receptor binding
          protein binding
          signaling receptor activity
          identical protein binding
          protein heterodimerization activity
          NAD+ nucleotidase, cyclic ADP-ribose generating

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