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          System Message

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          LOADING ...
          See other ERBB2 SIRNA Assays ›
          Gene Symbol:
          ERBB2
          Gene Name:
          erb-b2 receptor tyrosine kinase 2
          Gene Aliases:
          CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
          Chromosome Location:
          Chr.17: 39688084 - 39728662 on Build GRCh38
          UniGene ID:
          Hs.446352
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 103761

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ERBB2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001005862.2 NP_001005862.1 24, 25 3143
          NM_001289936.1 NP_001276865.1 25, 26 3194
          NM_001289937.1 NP_001276866.1 21, 22 2918
          NM_004448.3 NP_004439.2 21, 22 2918
          NR_110535.1 21, 22 2981
          GenBank mRNA AK295195.1 - 25, 26 3194
          AK300321.1 - 15, 16 2092
          AK313683.1 - 21, 22 2872
          BC080193.1 - 21, 22 2879
          BC167147.1 - 21, 22 2660 100013444
          KJ534831.1 - 21, 22 2657
          M11730.1 - 21, 22 2807
          X03363.1 - 21, 22 2831

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_001003817, AK129487, AK083669, BC053078, U71126, and others.

          Panther Classification:

          Molecular Function -

          transmembrane signal receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          positive regulation of protein phosphorylation
          transcription, DNA-templated
          protein phosphorylation
          signal transduction
          cell surface receptor signaling pathway
          enzyme linked receptor protein signaling pathway
          transmembrane receptor protein tyrosine kinase signaling pathway
          peripheral nervous system development
          heart development
          neuromuscular junction development
          motor neuron axon guidance
          cell proliferation
          phosphatidylinositol 3-kinase signaling
          regulation of phosphatidylinositol 3-kinase signaling
          peptidyl-tyrosine phosphorylation
          positive regulation of cell growth
          regulation of microtubule-based process
          negative regulation of immature T cell proliferation in thymus
          ERBB2 signaling pathway
          wound healing
          myelination
          positive regulation of MAP kinase activity
          positive regulation of GTPase activity
          positive regulation of translation
          regulation of angiogenesis
          positive regulation of cell adhesion
          positive regulation of transcription from RNA polymerase I promoter
          positive regulation of transcription from RNA polymerase III promoter
          protein autophosphorylation
          phosphatidylinositol phosphorylation
          phosphatidylinositol-mediated signaling
          oligodendrocyte differentiation
          positive regulation of epithelial cell proliferation
          regulation of ERK1 and ERK2 cascade
          cellular response to growth factor stimulus
          cellular response to epidermal growth factor stimulus
          positive regulation of protein targeting to membrane
          regulation of cell motility
          RNA polymerase I core binding
          protein tyrosine kinase activity
          transmembrane receptor protein tyrosine kinase activity
          receptor signaling protein tyrosine kinase activity
          transmembrane signaling receptor activity
          Ras guanyl-nucleotide exchange factor activity
          protein binding
          ATP binding
          protein C-terminus binding
          growth factor binding
          protein phosphatase binding
          identical protein binding
          ErbB-3 class receptor binding
          phosphatidylinositol-4,5-bisphosphate 3-kinase activity
          protein heterodimerization activity
          protein dimerization activity

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