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          System Message

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          LOADING ...
          See other EGFR SIRNA Assays ›
          Gene Symbol:
          EGFR
          Gene Name:
          epidermal growth factor receptor
          Gene Aliases:
          ERBB, ERBB1, HER1, NISBD2, PIG61, mENA
          Chromosome Location:
          Chr.7: 55019032 - 55207338 on Build GRCh38
          UniGene ID:
          Hs.488293
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 103768

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: EGFR
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_005228.3 NP_005219.2 5, 6 866
          NM_201282.1 NP_958439.1 5, 6 866
          NM_201283.1 NP_958440.1 5, 6 866
          NM_201284.1 NP_958441.1 5, 6 866
          GenBank mRNA AB209442.1 - 5, 6 765
          AF125253.1 - 5, 6 865
          AK225422.1 - 5, 6 781
          AK290352.1 - 5, 6 666
          AK294750.1 - 5, 6 644
          AY550966.1 - 5, 6 666
          AY698023.1 - 5, 6 620
          AY698024.1 - 5, 6 620
          BC094761.1 - 4, 5 742 30528231
          DQ088980.1 - 5, 6 666
          GU255993.1 - 5, 6 663
          HQ912715.1 - 4, 5 731
          K03193.1 - 5, 6 779
          U48722.1 - 5, 6 864
          U95089.1 - 6, 7 1123
          X00588.1 - 5, 6 806
          X00663.1 - 2, 3 194

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          More Information


          Panther Classification:

          Molecular Function -

          transmembrane signal receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          activation of MAPKK activity
          cell morphogenesis
          ossification
          embryonic placenta development
          positive regulation of protein phosphorylation
          hair follicle development
          response to stress
          signal transduction
          cell surface receptor signaling pathway
          epidermal growth factor receptor signaling pathway
          activation of phospholipase C activity
          salivary gland morphogenesis
          learning or memory
          cell proliferation
          positive regulation of cell proliferation
          regulation of phosphatidylinositol 3-kinase signaling
          single organismal cell-cell adhesion
          peptidyl-tyrosine phosphorylation
          cerebral cortex cell migration
          positive regulation of cell growth
          positive regulation of cell migration
          positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
          positive regulation of catenin import into nucleus
          ERBB2 signaling pathway
          negative regulation of epidermal growth factor receptor signaling pathway
          negative regulation of protein catabolic process
          positive regulation of phosphorylation
          activation of phospholipase A2 activity by calcium-mediated signaling
          negative regulation of apoptotic process
          positive regulation of MAP kinase activity
          positive regulation of GTPase activity
          positive regulation of nitric oxide biosynthetic process
          positive regulation of DNA repair
          positive regulation of DNA replication
          positive regulation of transcription from RNA polymerase II promoter
          protein autophosphorylation
          phosphatidylinositol phosphorylation
          phosphatidylinositol-mediated signaling
          positive regulation of fibroblast proliferation
          digestive tract morphogenesis
          positive regulation of epithelial cell proliferation
          regulation of peptidyl-tyrosine phosphorylation
          regulation of nitric-oxide synthase activity
          protein insertion into membrane
          positive regulation of protein kinase B signaling
          morphogenesis of an epithelial fold
          eyelid development in camera-type eye
          response to UV-A
          positive regulation of ERK1 and ERK2 cascade
          cellular response to amino acid stimulus
          cellular response to epidermal growth factor stimulus
          cellular response to estradiol stimulus
          positive regulation of production of miRNAs involved in gene silencing by miRNA
          regulation of cell motility
          chromatin binding
          double-stranded DNA binding
          MAP kinase kinase kinase activity
          protein tyrosine kinase activity
          transmembrane receptor protein tyrosine kinase activity
          receptor signaling protein tyrosine kinase activity
          transmembrane signaling receptor activity
          epidermal growth factor-activated receptor activity
          Ras guanyl-nucleotide exchange factor activity
          protein binding
          ATP binding
          enzyme binding
          protein phosphatase binding
          nitric-oxide synthase regulator activity
          ubiquitin protein ligase binding
          identical protein binding
          phosphatidylinositol-4,5-bisphosphate 3-kinase activity
          protein heterodimerization activity
          actin filament binding
          cadherin binding involved in cell-cell adhesion

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