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          System Message

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          LOADING ...
          See other PTPN22 SIRNA Assays ›
          Gene Symbol:
          PTPN22
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 22
          Gene Aliases:
          LYP, LYP1, LYP2, PEP, PTPN8
          Chromosome Location:
          Chr.1: 113813811 - 113871761 on Build GRCh38
          UniGene ID:
          Hs.535276
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 114800

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PTPN22
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001193431.2 NP_001180360.1 1, 2 234
          NM_001308297.1 NP_001295226.1 1, 2 234
          NM_012411.5 NP_036543.4 1, 2 234
          NM_015967.6 NP_057051.3 1, 2 234
          XM_011541221.1 XP_011539523.1 1, 2 215
          XM_011541222.1 XP_011539524.1 1, 2 215
          XM_011541223.2 XP_011539525.1 1, 2 215
          XM_011541225.2 XP_011539527.1 1, 2 236
          XM_017001004.1 XP_016856493.1 1, 2 215
          XM_017001005.1 XP_016856494.1 1, 2 196
          XM_017001006.1 XP_016856495.1 1, 2 215
          GenBank mRNA AF001846.1 - 1, 2 139
          AF077031.1 - 1, 2 170
          AF150732.1 - 1, 2 168
          AK303124.1 - 1, 2 183
          AK310570.1 - 1, 2 187
          AK310698.1 - 1, 2 187
          BC017785.1 - 1, 2 187
          BC071670.1 - 1, 2 173 5497108
          CD692658.1 - 1, 2 254
          DB145424.1 - 2, 3 413
          DN997966.1 - 1, 2 144
          GU479452.1 - 1, 2 148
          JN084012.1 - 1, 2 111

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001106460, XM_006233072, XM_008761379.

          Gene Ontology Categories:

          Function(s) Process(es)

          protein dephosphorylation
          autophagy
          negative regulation of autophagy
          positive regulation of gene expression
          negative regulation of gene expression
          T cell differentiation
          lipopolysaccharide-mediated signaling pathway
          positive regulation of type I interferon production
          response to lipopolysaccharide
          negative regulation of tumor necrosis factor production
          regulation of natural killer cell proliferation
          positive regulation of toll-like receptor 3 signaling pathway
          positive regulation of toll-like receptor 4 signaling pathway
          peptidyl-tyrosine dephosphorylation
          phosphoanandamide dephosphorylation
          negative regulation of JUN kinase activity
          regulation of innate immune response
          regulation of B cell receptor signaling pathway
          negative regulation of T cell receptor signaling pathway
          negative regulation of T cell activation
          positive regulation of ERK1 and ERK2 cascade
          negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
          cellular response to muramyl dipeptide
          negative regulation of interleukin-6 secretion
          regulation of NIK/NF-kappaB signaling
          positive regulation of protein K63-linked ubiquitination
          positive regulation of interferon-gamma secretion
          negative regulation of p38MAPK cascade
          negative regulation of interleukin-8 secretion
          protein tyrosine phosphatase activity
          protein binding
          phosphatase activity
          SH3 domain binding
          kinase binding
          ubiquitin protein ligase binding

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