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See other SMAD4 SIRNA Assays ›
Gene Symbol:
SMAD4
Gene Name:
SMAD family member 4
Gene Aliases:
DPC4, JIP, MADH4, MYHRS
Chromosome Location:
Chr.18: 51030213 - 51085042 on Build GRCh38
UniGene ID:
Hs.75862
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID
115650
Purification
Standard
HPLC
In-Vivo Ready
Size
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
Availability
Inventoried
Catalog #
AM16708
Price
Your Price
Online offer:
Check your price ›
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Genomic Map
siRNA Details
More Information
Genomic Map
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siRNA Details
Gene Symbol: SMAD4
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_005359.5
NP_005350.1
12
2614
GenBank mRNA
BC002379.2
-
13
2309
2961238
BX647129.1
-
8
4078
U44378.1
-
11
2203
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More Information
Panther Classification:
Molecular Function -
DNA-binding transcription factor
gene-specific transcriptional regulator
Gene Ontology Categories:
Function(s)
Process(es)
negative regulation of transcription from RNA polymerase II promoter
ovarian follicle development
branching involved in ureteric bud morphogenesis
response to hypoxia
in utero embryonic development
gastrulation with mouth forming second
atrioventricular valve formation
epithelial to mesenchymal transition involved in endocardial cushion formation
left ventricular cardiac muscle tissue morphogenesis
positive regulation of cell proliferation involved in heart valve morphogenesis
brainstem development
transcription from RNA polymerase II promoter
cellular iron ion homeostasis
transforming growth factor beta receptor signaling pathway
SMAD protein complex assembly
spermatogenesis
single fertilization
axon guidance
endoderm development
mesoderm development
cell proliferation
negative regulation of cell proliferation
negative regulation of cardiac muscle hypertrophy
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
neural crest cell differentiation
regulation of transforming growth factor beta receptor signaling pathway
negative regulation of cell growth
BMP signaling pathway
positive regulation of transforming growth factor beta receptor signaling pathway
positive regulation of BMP signaling pathway
somite rostral/caudal axis specification
regulation of transforming growth factor beta2 production
positive regulation of luteinizing hormone secretion
somatic stem cell population maintenance
intracellular signal transduction
atrioventricular canal development
endothelial cell activation
embryonic digit morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of follicle-stimulating hormone secretion
developmental growth
neuron fate commitment
sebaceous gland development
formation of anatomical boundary
regulation of binding
positive regulation of histone H3-K4 methylation
regulation of hair follicle development
palate development
uterus development
positive regulation of SMAD protein import into nucleus
SMAD protein signal transduction
ventricular septum morphogenesis
negative regulation of cell death
endocardial cell differentiation
female gonad morphogenesis
interleukin-6-mediated signaling pathway
negative regulation of ERK1 and ERK2 cascade
response to transforming growth factor beta
cellular response to BMP stimulus
metanephric mesenchyme morphogenesis
nephrogenic mesenchyme morphogenesis
seminiferous tubule development
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
positive regulation of histone H3-K9 acetylation
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcription factor activity, protein binding
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
collagen binding
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
protein heterodimerization activity
I-SMAD binding
R-SMAD binding
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