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          System Message

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          LOADING ...
          See other EIF2AK3 SIRNA Assays ›
          Gene Symbol:
          EIF2AK3
          Gene Name:
          eukaryotic translation initiation factor 2 alpha kinase 3
          Gene Aliases:
          PEK, PERK, WRS
          Chromosome Location:
          Chr.2: 88556740 - 88627576 on Build GRCh38
          UniGene ID:
          Hs.591589
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 137755

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: EIF2AK3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001313915.1 NP_001300844.1 4 601
          NM_004836.6 NP_004827.4 4 1027
          XM_017005376.1 XP_016860865.1 5 919
          GenBank mRNA AF110146.1 - 4 794
          AF193339.1 - 4 1024
          AK128659.1 - 5 780
          AK308312.1 - 3 395
          AK315287.1 - 4 932
          BC126354.1 - 4 821 8992070
          BC126356.1 - 4 818 8992072
          CN285475.1 - 3 354
          CR749382.1 - 4 602

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          More Information


          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          skeletal system development
          ossification
          angiogenesis
          chondrocyte development
          protein phosphorylation
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          ER overload response
          endoplasmic reticulum organization
          positive regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          regulation of translational initiation by eIF2 alpha phosphorylation
          negative regulation of translation
          peptidyl-serine phosphorylation
          calcium-mediated signaling
          insulin secretion
          bone mineralization
          endoplasmic reticulum unfolded protein response
          endocrine pancreas development
          negative regulation of myelination
          negative regulation of translational initiation in response to stress
          cellular response to amino acid starvation
          response to endoplasmic reticulum stress
          eiF2alpha phosphorylation in response to endoplasmic reticulum stress
          PERK-mediated unfolded protein response
          cellular response to glucose starvation
          positive regulation of transcription from RNA polymerase I promoter
          protein autophosphorylation
          insulin-like growth factor receptor signaling pathway
          protein homooligomerization
          regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
          cellular response to cold
          positive regulation of protein localization to nucleus
          regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          response to manganese-induced endoplasmic reticulum stress
          protein kinase activity
          protein serine/threonine kinase activity
          eukaryotic translation initiation factor 2alpha kinase activity
          protein binding
          ATP binding
          enzyme binding
          protein phosphatase binding
          identical protein binding
          protein homodimerization activity
          Hsp90 protein binding

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