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          System Message

          OKCancel
          LOADING ...
          See other PDE4D SIRNA Assays ›
          Gene Symbol:
          PDE4D
          Gene Name:
          phosphodiesterase 4D
          Gene Aliases:
          ACRDYS2, DPDE3, HSPDE4D, PDE43, PDE4DN2, STRK1
          Chromosome Location:
          Chr.5: 58969038 - 60488098 on Build GRCh38
          UniGene ID:
          Hs.117545
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 144230

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PDE4D
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001104631.1 NP_001098101.1 2 770
          NM_001165899.1 NP_001159371.1 4 661
          NM_001197218.1 NP_001184147.1 2 509
          NM_001197219.1 NP_001184148.1 2 287
          NM_001197220.1 NP_001184149.1 2 925
          NM_006203.4 NP_006194.2 2 313
          XM_005248537.3 XP_005248594.1 2 1467
          XM_005248538.4 XP_005248595.1 3 3368
          XM_011543469.1 XP_011541771.1 5 750
          XM_011543470.2 XP_011541772.1 5 674
          XM_011543471.1 XP_011541773.1 4 627
          XM_011543473.1 XP_011541775.1 4 575
          XM_011543477.2 XP_011541779.1 4 577
          XM_017009565.1 XP_016865054.1 5 787
          XM_017009566.1 XP_016865055.1 5 677
          XM_017009567.1 XP_016865056.1 3 415
          XM_017009568.1 XP_016865057.1 5 661
          XM_017009569.1 XP_016865058.1 4 540
          XM_017009570.1 XP_016865059.1 2 1434
          XM_017009571.1 XP_016865060.1 5 657
          GenBank mRNA AF012073.1 - 2 523
          AF536976.1 - 3 484
          AF536977.1 - 2 287
          AJ250854.1 - 2 406
          AJ250855.1 - 2 261
          AY245866.1 - 4 626
          AY245867.1 - 2 925
          AY388960.1 - 2 208
          BC008390.1 - 2 533
          BT007398.1 - 2 406
          L20970.1 - 2 321
          U02882.1 - 1 91
          U50159.1 - 2 264

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001113328, NM_001113329, NM_001113334, NM_017032, NM_001113332, and others.

          Panther Classification:

          Molecular Function -

          phosphodiesterase

          Gene Ontology Categories:

          Function(s) Process(es)

          regulation of heart rate
          cAMP catabolic process
          smooth muscle contraction
          aging
          regulation of receptor activity
          regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
          cAMP-mediated signaling
          neutrophil chemotaxis
          regulation of cAMP metabolic process
          positive regulation of interferon-gamma production
          positive regulation of interleukin-2 production
          positive regulation of interleukin-5 production
          negative regulation of peptidyl-serine phosphorylation
          multicellular organism growth
          negative regulation of heart contraction
          T cell receptor signaling pathway
          regulation of ryanodine-sensitive calcium-release channel activity
          establishment of endothelial barrier
          cellular response to lipopolysaccharide
          cellular response to epinephrine stimulus
          adrenergic receptor signaling pathway
          regulation of cardiac muscle cell contraction
          adrenergic receptor signaling pathway involved in positive regulation of heart rate
          regulation of cell communication by electrical coupling involved in cardiac conduction
          negative regulation of relaxation of cardiac muscle
          3',5'-cyclic-nucleotide phosphodiesterase activity
          3',5'-cyclic-AMP phosphodiesterase activity
          protein binding
          drug binding
          enzyme binding
          cAMP binding
          beta-2 adrenergic receptor binding
          ion channel binding
          metal ion binding
          ATPase binding
          scaffold protein binding

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          Host server : magellan-search-green-55658555d6-72rkq:80/100.66.79.224:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline