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          System Message

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          LOADING ...
          See other MSH2 SIRNA Assays ›
          Gene Symbol:
          Msh2
          Gene Name:
          mutS homolog 2 (E. coli)
          Gene Aliases:
          AI788990
          Chromosome Location:
          Chr.17: 87672557 - 87723713 on Build GRCm38
          UniGene ID:
          Mm.4619
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 155432

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Msh2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_008628.2 NP_032654.1 4 708
          GenBank mRNA AK051960.1 - 4 705
          AK157842.1 - 4 721
          BC047117.1 - 4 716 4951173
          BC050897.1 - 4 691 6401835
          U21011.1 - 4 725
          X81143.1 - 4 708

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_031058, BC161846, X93591.

          Panther Classification:

          Molecular Function -

          DNA metabolism protein

          Gene Ontology Categories:

          Function(s) Process(es)

          meiotic mismatch repair
          in utero embryonic development
          somatic recombination of immunoglobulin genes involved in immune response
          oxidative phosphorylation
          DNA repair
          mismatch repair
          postreplication repair
          double-strand break repair
          meiotic gene conversion
          cellular response to DNA damage stimulus
          cell cycle
          cell cycle arrest
          reciprocal meiotic recombination
          germ cell development
          determination of adult lifespan
          male gonad development
          intrinsic apoptotic signaling pathway in response to DNA damage
          response to X-ray
          response to UV-B
          somatic hypermutation of immunoglobulin genes
          somatic recombination of immunoglobulin gene segments
          B cell mediated immunity
          B cell differentiation
          intra-S DNA damage checkpoint
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          negative regulation of neuron apoptotic process
          maintenance of DNA repeat elements
          negative regulation of reciprocal meiotic recombination
          isotype switching
          negative regulation of DNA recombination
          positive regulation of helicase activity
          nucleotide binding
          magnesium ion binding
          four-way junction DNA binding
          Y-form DNA binding
          heteroduplex DNA loop binding
          double-strand/single-strand DNA junction binding
          DNA binding
          damaged DNA binding
          double-stranded DNA binding
          single-stranded DNA binding
          ATP binding
          protein C-terminus binding
          DNA-dependent ATPase activity
          ATPase activity
          centromeric DNA binding
          enzyme binding
          protein kinase binding
          mismatched DNA binding
          guanine/thymine mispair binding
          single base insertion or deletion binding
          dinucleotide insertion or deletion binding
          single guanine insertion binding
          single thymine insertion binding
          dinucleotide repeat insertion binding
          oxidized purine DNA binding
          MutLalpha complex binding
          protein homodimerization activity
          ADP binding

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