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          System Message

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          LOADING ...
          See other TOP2A SIRNA Assays ›
          Gene Symbol:
          Top2a
          Gene Name:
          topoisomerase (DNA) II alpha
          Gene Aliases:
          -
          Chromosome Location:
          Chr.10: 86901467 - 86930947 on Build Rnor_6.0
          UniGene ID:
          Rn.90996
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID 189259

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Top2a
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_022183.2 NP_071519.2 1, 2 182
          GenBank mRNA Z19552.1 - 1, 2 182

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Human: NM_001067, BC140791, AF285159, J04088, AF285158, and others.
          This siRNA also targets the following transcripts in Mouse: NM_011623, D12513, BC057873.

          Panther Classification:

          Molecular Function -

          DNA metabolism protein

          Gene Ontology Categories:

          Function(s) Process(es)

          resolution of meiotic recombination intermediates
          sister chromatid segregation
          hematopoietic progenitor cell differentiation
          DNA topological change
          DNA ligation
          DNA unwinding involved in DNA replication
          mitotic recombination
          cellular response to DNA damage stimulus
          chromosome segregation
          brain development
          aging
          cerebellar Purkinje cell differentiation
          cerebellar granule cell differentiation
          chromosome condensation
          apoptotic chromosome condensation
          embryonic cleavage
          response to drug
          regulation of circadian rhythm
          positive regulation of apoptotic process
          mitotic DNA integrity checkpoint
          positive regulation of viral genome replication
          positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
          positive regulation of transcription from RNA polymerase II promoter
          rhythmic process
          response to parathyroid hormone
          magnesium ion binding
          DNA binding
          chromatin binding
          DNA topoisomerase activity
          DNA topoisomerase type II (ATP-hydrolyzing) activity
          protein kinase C binding
          ATP binding
          protein C-terminus binding
          DNA-dependent ATPase activity
          drug binding
          DNA binding, bending
          enzyme binding
          protein homodimerization activity
          histone deacetylase binding
          ubiquitin binding
          sequence-specific DNA binding
          structure-specific DNA binding
          poly(A) RNA binding
          protein heterodimerization activity

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