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          System Message

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          LOADING ...
          See other LYN SIRNA Assays ›
          Gene Symbol:
          LYN
          Gene Name:
          LYN proto-oncogene, Src family tyrosine kinase
          Gene Aliases:
          JTK8, p53Lyn, p56Lyn
          Chromosome Location:
          Chr.8: 55877305 - 56012447 on Build GRCh38
          UniGene ID:
          Hs.491767
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 228

          Purification
          Size
          Availability Inventoried
          Catalog # AM51331
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: LYN
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001111097.2 NP_001104567.1 11, 12 1426
          NM_002350.3 NP_002341.1 11, 12 1489
          XM_011517529.2 XP_011515831.1 10, 11 3874
          XM_017013416.1 XP_016868905.1 11, 12 1165
          GenBank mRNA AK130135.1 - 5, 6 590
          AK290494.1 - 11, 12 1399
          AK298677.1 - 9, 10 1077
          BC059394.1 - 11, 12 1418
          BC068551.1 - 11, 12 1418
          BC075001.2 - 10, 11 1232 30915399
          BC075002.2 - 10, 11 1232 30915611
          BC126456.1 - 12, 13 1326 8992172
          BC126458.1 - 12, 13 1373 8992174
          M16038.1 - 11, 12 1504
          M79321.1 - 10, 11 1168

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          B cell homeostasis
          regulation of cytokine production
          regulation of protein phosphorylation
          negative regulation of protein phosphorylation
          stimulatory C-type lectin receptor signaling pathway
          adaptive immune response
          Fc receptor mediated stimulatory signaling pathway
          tolerance induction to self antigen
          histamine secretion by mast cell
          platelet degranulation
          negative regulation of myeloid leukocyte differentiation
          immune response-regulating cell surface receptor signaling pathway
          Fc receptor mediated inhibitory signaling pathway
          regulation of B cell apoptotic process
          protein phosphorylation
          inflammatory response
          cellular response to DNA damage stimulus
          response to sterol depletion
          signal transduction
          transmembrane receptor protein tyrosine kinase signaling pathway
          central nervous system development
          blood coagulation
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          response to toxic substance
          response to hormone
          response to carbohydrate
          positive regulation of neuron projection development
          oligodendrocyte development
          response to organic cyclic compound
          viral process
          peptidyl-tyrosine phosphorylation
          signal transduction by protein phosphorylation
          platelet activation
          erythrocyte differentiation
          positive regulation of cell migration
          negative regulation of B cell proliferation
          neuron projection development
          T cell costimulation
          lipopolysaccharide-mediated signaling pathway
          cellular response to extracellular stimulus
          response to insulin
          regulation of mast cell activation
          regulation of cell adhesion mediated by integrin
          negative regulation of toll-like receptor 2 signaling pathway
          negative regulation of toll-like receptor 4 signaling pathway
          cellular response to heat
          peptidyl-tyrosine autophosphorylation
          Fc-epsilon receptor signaling pathway
          Fc-gamma receptor signaling pathway involved in phagocytosis
          response to drug
          positive regulation of tyrosine phosphorylation of STAT protein
          response to amino acid
          regulation of mast cell degranulation
          negative regulation of MAP kinase activity
          positive regulation of phosphatidylinositol 3-kinase activity
          innate immune response
          regulation of erythrocyte differentiation
          protein autophosphorylation
          ephrin receptor signaling pathway
          response to axon injury
          cytokine secretion
          regulation of cytokine secretion
          regulation of inflammatory response
          negative regulation of immune response
          B cell receptor signaling pathway
          regulation of B cell receptor signaling pathway
          positive regulation of B cell receptor signaling pathway
          leukocyte migration
          positive regulation of cellular component movement
          regulation of release of sequestered calcium ion into cytosol
          positive regulation of glial cell proliferation
          positive regulation of Fc receptor mediated stimulatory signaling pathway
          JAK-STAT cascade involved in growth hormone signaling pathway
          positive regulation of stress-activated protein kinase signaling cascade
          regulation of ERK1 and ERK2 cascade
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of oligodendrocyte progenitor proliferation
          negative regulation of mast cell proliferation
          positive regulation of mast cell proliferation
          cellular response to retinoic acid
          regulation of monocyte chemotaxis
          regulation of platelet aggregation
          dendritic cell differentiation
          negative regulation of intracellular signal transduction
          positive regulation of dendritic cell apoptotic process
          protein tyrosine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          receptor signaling protein tyrosine kinase activity
          receptor binding
          platelet-derived growth factor receptor binding
          integrin binding
          protein binding
          ATP binding
          SH3 domain binding
          ubiquitin protein ligase binding
          gamma-tubulin binding
          glycosphingolipid binding
          ion channel binding
          phosphoprotein binding

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          Host server : magellan-search-green-55658555d6-7g8vv:80/100.66.77.153:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline