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          System Message

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          LOADING ...
          See other RAPGEF2 SIRNA Assays ›
          Gene Symbol:
          RAPGEF2
          Gene Name:
          Rap guanine nucleotide exchange factor 2
          Gene Aliases:
          CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, RA-GEF-1, Rap-GEP, nRap GEP
          Chromosome Location:
          Chr.4: 159104067 - 159360164 on Build GRCh38
          UniGene ID:
          Hs.744884
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 272488

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: RAPGEF2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_014247.2 NP_055062.1 10 1653
          XM_005263358.3 XP_005263415.1 16 1920
          XM_005263359.3 XP_005263416.1 16 1922
          XM_005263360.3 XP_005263417.1 16 1914
          XM_005263361.3 XP_005263418.1 15 1902
          XM_006714420.3 XP_006714483.1 15 1902
          XM_006714421.3 XP_006714484.1 16 1887
          XM_006714422.3 XP_006714485.1 13 2135
          XM_011532425.2 XP_011530727.1 12 1750
          XM_011532426.2 XP_011530728.1 13 2687
          XM_011532427.2 XP_011530729.1 10 2337
          XM_017008856.1 XP_016864345.1 16 1921
          XM_017008857.1 XP_016864346.1 13 2686
          XM_017008858.1 XP_016864347.1 13 1654
          XM_017008859.1 XP_016864348.1 10 2337
          GenBank mRNA AB002311.1 - 10 1405
          AK294459.1 - 10 1654
          BC117321.1 - 10 1331 40125872

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          More Information


          Panther Classification:

          Molecular Function -

          guanyl-nucleotide exchange factor

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          blood vessel development
          neuron migration
          G-protein coupled receptor signaling pathway
          neuropeptide signaling pathway
          small GTPase mediated signal transduction
          negative regulation of cell proliferation
          positive regulation of neuron projection development
          cAMP-mediated signaling
          ventricular system development
          forebrain neuron development
          microvillus assembly
          neuron projection development
          brain-derived neurotrophic factor receptor signaling pathway
          positive regulation of protein binding
          Rap protein signal transduction
          intracellular signal transduction
          nerve growth factor signaling pathway
          positive regulation of GTPase activity
          positive regulation of cAMP-mediated signaling
          positive regulation of protein kinase activity
          negative regulation of melanin biosynthetic process
          regulation of synaptic plasticity
          negative regulation of dendrite morphogenesis
          establishment of endothelial barrier
          positive regulation of ERK1 and ERK2 cascade
          cellular response to cAMP
          cellular response to cGMP
          adenylate cyclase-activating adrenergic receptor signaling pathway
          protein localization to plasma membrane
          establishment of endothelial intestinal barrier
          regulation of cell junction assembly
          cellular response to nerve growth factor stimulus
          positive regulation of cAMP-dependent protein kinase activity
          positive regulation of dendritic cell apoptotic process
          positive regulation of vasculogenesis
          positive regulation of neuron migration
          signal transducer activity
          Ras guanyl-nucleotide exchange factor activity
          GTPase activator activity
          calcium ion binding
          protein binding
          Rap guanyl-nucleotide exchange factor activity
          diacylglycerol binding
          PDZ domain binding
          cAMP binding
          cGMP binding
          beta-1 adrenergic receptor binding
          WW domain binding
          phosphatidic acid binding

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