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          System Message

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          LOADING ...
          See other DDIT3 SIRNA Assays ›
          Gene Symbol:
          Ddit3
          Gene Name:
          DNA-damage inducible transcript 3
          Gene Aliases:
          CHOP-10, CHOP10, chop, gadd153
          Chromosome Location:
          Chr.10: 127290793 - 127296288 on Build GRCm38
          UniGene ID:
          Mm.110220
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 288791

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Ddit3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001290183.1 NP_001277112.1 2 185
          NM_007837.4 NP_031863.3 3 233
          GenBank mRNA AA929408.1 - 2 164
          AK028120.1 - 3 230
          BC013718.1 - 3 228 4012433
          BY121546.1 - 3 233
          X67083.1 - 2 140

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001109986, NM_024134, XM_006241445, XM_006241444, AW916370, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          blood vessel maturation
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          apoptotic process
          ER overload response
          response to unfolded protein
          cell cycle
          cell cycle arrest
          Wnt signaling pathway
          endoplasmic reticulum unfolded protein response
          positive regulation of interleukin-8 production
          negative regulation of CREB transcription factor activity
          response to endoplasmic reticulum stress
          response to starvation
          mRNA transcription from RNA polymerase II promoter
          positive regulation of apoptotic process
          proteasome-mediated ubiquitin-dependent protein catabolic process
          negative regulation of DNA binding
          negative regulation of sequence-specific DNA binding transcription factor activity
          positive regulation of neuron apoptotic process
          regulation of transcription involved in anterior/posterior axis specification
          cell redox homeostasis
          negative regulation of fat cell differentiation
          negative regulation of myoblast differentiation
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          release of sequestered calcium ion into cytosol
          negative regulation of protein kinase B signaling
          intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
          negative regulation of canonical Wnt signaling pathway
          positive regulation of neuron death
          negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
          positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
          negative regulation of determination of dorsal identity
          transcription regulatory region sequence-specific DNA binding
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          transcription factor binding
          cAMP response element binding protein binding
          leucine zipper domain binding
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          protein heterodimerization activity

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