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          System Message

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          LOADING ...
          See other BMP4 SIRNA Assays ›
          Gene Symbol:
          BMP4
          Gene Name:
          bone morphogenetic protein 4
          Gene Aliases:
          BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
          Chromosome Location:
          Chr.14: 53949736 - 53956862 on Build GRCh38
          UniGene ID:
          Hs.68879
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 4035

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 283.00
          Your Price
          Online offer: 274.65
          274.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: BMP4
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001202.4 NP_001193.2 4 1211
          NM_130850.3 NP_570911.2 4 1002
          XM_005268015.4 XP_005268072.1 4 2415
          XM_017021603.1 XP_016877092.1 4 991
          XM_017021604.1 XP_016877093.1 4 1118
          XM_017021605.1 XP_016877094.1 4 1265
          GenBank mRNA BC020546.2 - 4 967 4399276
          BX161385.1 - 3 953
          BX161438.1 - 4 958
          D30751.1 - 2 849
          KM220602.1 - 3 874
          M22490.1 - 4 1160

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012827, XM_006251748, XM_006251746, XM_006251749, XM_008770501, and others.

          Panther Classification:

          Molecular Function -

          growth factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          activation of MAPKK activity
          ovarian follicle development
          osteoblast differentiation
          ureteric bud development
          branching involved in ureteric bud morphogenesis
          kidney development
          mesonephros development
          neural tube closure
          positive regulation of protein phosphorylation
          positive regulation of endothelial cell proliferation
          endochondral ossification
          blood vessel endothelial cell proliferation involved in sprouting angiogenesis
          chondrocyte differentiation
          hematopoietic progenitor cell differentiation
          lymphoid progenitor cell differentiation
          renal system process
          BMP signaling pathway involved in heart induction
          secondary heart field specification
          outflow tract septum morphogenesis
          membranous septum morphogenesis
          muscular septum morphogenesis
          aortic valve morphogenesis
          pulmonary valve morphogenesis
          endocardial cushion development
          epithelial to mesenchymal transition involved in endocardial cushion formation
          cardiac right ventricle morphogenesis
          apoptotic process involved in endocardial cushion morphogenesis
          cardiac septum development
          type B pancreatic cell development
          mesenchymal to epithelial transition involved in metanephros morphogenesis
          common-partner SMAD protein phosphorylation
          smoothened signaling pathway
          germ cell development
          mesodermal cell fate determination
          negative regulation of cell proliferation
          post-embryonic development
          anterior/posterior axis specification
          specification of organ position
          regulation of cell fate commitment
          positive regulation of calcium ion transport into cytosol
          positive regulation of endothelial cell migration
          positive regulation of pathway-restricted SMAD protein phosphorylation
          positive regulation of cell death
          positive regulation of neuron projection development
          telencephalon development
          dorsal/ventral neural tube patterning
          telencephalon regionalization
          pituitary gland development
          erythrocyte differentiation
          monocyte differentiation
          macrophage differentiation
          positive regulation of bone mineralization
          BMP signaling pathway
          positive regulation of BMP signaling pathway
          positive regulation of protein binding
          negative regulation of chondrocyte differentiation
          response to estradiol
          response to retinoic acid
          positive regulation of collagen biosynthetic process
          negative regulation of T cell differentiation in thymus
          negative regulation of immature T cell proliferation in thymus
          response to testosterone
          protein localization to nucleus
          cellular response to oxidative stress
          embryonic hindlimb morphogenesis
          tendon cell differentiation
          deltoid tuberosity development
          wound healing
          regulation of protein import into nucleus
          negative regulation of phosphorylation
          odontogenesis of dentin-containing tooth
          odontogenesis
          regulation of odontogenesis of dentin-containing tooth
          embryonic digit morphogenesis
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          steroid hormone mediated signaling pathway
          negative regulation of MAP kinase activity
          tongue morphogenesis
          positive regulation of endothelial cell differentiation
          positive regulation of epidermal cell differentiation
          negative regulation of myoblast differentiation
          positive regulation of osteoblast differentiation
          positive regulation of ossification
          negative regulation of cell cycle
          negative regulation of mitotic nuclear division
          negative regulation of striated muscle tissue development
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          lung alveolus development
          intermediate mesodermal cell differentiation
          positive regulation of smooth muscle cell proliferation
          neuron fate commitment
          embryonic cranial skeleton morphogenesis
          negative regulation of oligodendrocyte differentiation
          smooth muscle tissue development
          branching morphogenesis of an epithelial tube
          positive regulation of epithelial cell proliferation
          negative regulation of epithelial cell proliferation
          positive chemotaxis
          regulation of smooth muscle cell differentiation
          response to glucocorticoid
          positive regulation of cardiac muscle fiber development
          anatomical structure regression
          retina development in camera-type eye
          inner ear receptor cell differentiation
          cloacal septation
          lens induction in camera-type eye
          embryonic skeletal joint morphogenesis
          cranial suture morphogenesis
          positive regulation of SMAD protein import into nucleus
          regulation of pathway-restricted SMAD protein phosphorylation
          SMAD protein signal transduction
          lung morphogenesis
          bronchus development
          trachea development
          trachea formation
          epithelial tube branching involved in lung morphogenesis
          branching involved in prostate gland morphogenesis
          bud elongation involved in lung branching
          lung lobe development
          epithelial cell proliferation involved in lung morphogenesis
          bud dilation involved in lung branching
          negative regulation of cell death
          mammary gland formation
          epithelial-mesenchymal cell signaling
          negative regulation of prostatic bud formation
          regulation of branching involved in prostate gland morphogenesis
          coronary vasculature development
          positive regulation of cartilage development
          positive regulation of branching involved in lung morphogenesis
          BMP signaling pathway involved in ureter morphogenesis
          BMP signaling pathway involved in renal system segmentation
          pulmonary artery endothelial tube morphogenesis
          BMP signaling pathway involved in heart development
          pharyngeal arch artery morphogenesis
          negative regulation of thymocyte apoptotic process
          positive regulation of hepatocyte differentiation
          positive regulation of ERK1 and ERK2 cascade
          cellular response to mechanical stimulus
          response to nitric oxide
          cellular response to BMP stimulus
          BMP signaling pathway involved in nephric duct formation
          renal system development
          glomerular visceral epithelial cell development
          negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway
          specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
          glomerular capillary formation
          negative regulation of glomerular mesangial cell proliferation
          mesenchymal cell proliferation involved in ureteric bud development
          mesenchymal cell differentiation involved in kidney development
          ureter epithelial cell differentiation
          ureter smooth muscle cell differentiation
          mesenchymal cell proliferation involved in ureter development
          negative regulation of mesenchymal cell proliferation involved in ureter development
          metanephric collecting duct development
          positive regulation of kidney development
          negative regulation of branching involved in ureteric bud morphogenesis
          negative regulation of glomerulus development
          cellular response to thyroid hormone stimulus
          positive regulation of store-operated calcium channel activity
          positive regulation of cell proliferation involved in outflow tract morphogenesis
          positive regulation of mesenchymal stem cell proliferation
          cardiac jelly development
          negative regulation of metanephric S-shaped body morphogenesis
          negative regulation of metanephric comma-shaped body morphogenesis
          positive regulation of DNA-dependent DNA replication
          negative regulation of cell proliferation involved in heart morphogenesis
          positive regulation of endothelial cell apoptotic process
          negative regulation of extrinsic apoptotic signaling pathway
          cytokine activity
          transforming growth factor beta receptor binding
          protein binding
          growth factor activity
          heparin binding
          co-receptor binding
          chemoattractant activity
          protein homodimerization activity
          BMP receptor binding

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