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          System Message

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          LOADING ...
          See other PAX6 SIRNA Assays ›
          Gene Symbol:
          PAX6
          Gene Name:
          paired box 6
          Gene Aliases:
          AN, AN2, D11S812E, FVH1, MGDA, WAGR
          Chromosome Location:
          Chr.11: 31784792 - 31817961 on Build GRCh38
          UniGene ID:
          Hs.270303
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 4160

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PAX6
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000280.4 NP_000271.1 9, 10 1328
          NM_001127612.1 NP_001121084.1 9, 10 1242
          NM_001258462.1 NP_001245391.1 10, 11 1284
          NM_001258463.1 NP_001245392.1 10, 11 1222
          NM_001258464.1 NP_001245393.1 9, 10 1230
          NM_001258465.1 NP_001245394.1 8, 9 1216
          NM_001310158.1 NP_001297087.1 10, 11 1325
          NM_001310159.1 NP_001297088.1 7, 8 901
          NM_001310160.1 NP_001297089.1 6, 7 2539
          NM_001310161.1 NP_001297090.1 7, 8 1091
          NM_001604.5 NP_001595.2 10, 11 1272
          GenBank mRNA AB209177.1 - 7, 8 5680
          AB593092.1 - 10, 11 1223
          AB593093.1 - 10, 11 1222
          AB593094.1 - 10, 11 1325
          AK094172.1 - 4, 5 1966
          AK094249.1 - 6, 7 2349
          AK314470.1 - 9, 10 1220
          AY047583.1 - 7, 8 903
          AY707088.1 - 5, 6 773
          BC011953.1 - 9, 10 1114 3880468
          BX640762.1 - 10, 11 1251
          GQ141695.1 - 6, 7 821
          KP255960.1 - 6, 7 814
          M77844.1 - 8, 9 1135
          M93650.1 - 9, 10 1190

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_001244200, NM_001244198, NM_013627, NM_001244201, NM_001244202, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          establishment of mitotic spindle orientation
          blood vessel development
          eye development
          cell fate determination
          neuron migration
          negative regulation of protein phosphorylation
          positive regulation of neuroblast proliferation
          lens development in camera-type eye
          type B pancreatic cell differentiation
          pancreatic A cell development
          transcription from RNA polymerase II promoter
          smoothened signaling pathway
          axon guidance
          central nervous system development
          salivary gland morphogenesis
          visual perception
          response to wounding
          regulation of asymmetric cell division
          organ morphogenesis
          dorsal/ventral axis specification
          positive regulation of gene expression
          protein ubiquitination
          oligodendrocyte cell fate specification
          cerebral cortex regionalization
          forebrain anterior/posterior pattern specification
          forebrain dorsal/ventral pattern formation
          commitment of neuronal cell to specific neuron type in forebrain
          forebrain-midbrain boundary formation
          regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
          regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
          regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment
          pituitary gland development
          signal transduction involved in regulation of gene expression
          keratinocyte differentiation
          regulation of cell migration
          positive regulation of epithelial cell differentiation
          lacrimal gland development
          protein localization to organelle
          eye photoreceptor cell development
          glucose homeostasis
          negative regulation of neuron differentiation
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          regulation of timing of cell differentiation
          embryonic camera-type eye morphogenesis
          neuron fate commitment
          astrocyte differentiation
          negative regulation of epithelial cell proliferation
          negative regulation of neurogenesis
          retina development in camera-type eye
          iris morphogenesis
          cornea development in camera-type eye
          negative regulation of neural precursor cell proliferation
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          RNA polymerase II core promoter sequence-specific DNA binding
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
          DNA binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          ubiquitin-protein transferase activity
          protein binding
          transcription factor binding
          protein kinase binding
          ubiquitin protein ligase binding
          histone acetyltransferase binding
          co-SMAD binding
          R-SMAD binding
          HMG box domain binding

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