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          System Message

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          LOADING ...
          See other PTPN2 SIRNA Assays ›
          Gene Symbol:
          PTPN2
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 2
          Gene Aliases:
          PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP
          Chromosome Location:
          Chr.18: 12785478 - 12884351 on Build GRCh38
          UniGene ID:
          Hs.654527
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 4357

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PTPN2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001207013.1 NP_001193942.1 3 444
          NM_001308287.1 NP_001295216.1 2 339
          NM_002828.3 NP_002819.2 3 444
          NM_080422.2 NP_536347.1 3 444
          NM_080423.2 NP_536348.1 3 444
          XM_005258124.3 XP_005258181.1 3 442
          XM_005258125.3 XP_005258182.1 3 442
          XM_011525705.2 XP_011524007.1 4 662
          XM_011525706.2 XP_011524008.1 3 367
          XM_017025884.1 XP_016881373.1 3 460
          XM_017025885.1 XP_016881374.1 4 646
          XM_017025886.1 XP_016881375.1 2 334
          XM_017025887.1 XP_016881376.1 2 285
          XM_017025888.1 XP_016881377.1 2 285
          GenBank mRNA AB209569.1 - 2 371
          AK225706.1 - 3 323
          AK290649.1 - 3 326
          AK292570.1 - 3 344
          BC008244.1 - 3 287 3872164
          BC016727.1 - 3 356 4081330
          BG699440.1 - 3 449
          M25393.1 - 3 310

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          More Information


          Panther Classification:

          Molecular Function -

          protein phosphatase

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of cell proliferation
          insulin receptor signaling pathway
          negative regulation of tumor necrosis factor-mediated signaling pathway
          negative regulation of lipid storage
          B cell differentiation
          T cell differentiation
          erythrocyte differentiation
          peptidyl-tyrosine dephosphorylation
          negative regulation of epidermal growth factor receptor signaling pathway
          negative regulation of tyrosine phosphorylation of Stat1 protein
          negative regulation of tyrosine phosphorylation of Stat5 protein
          negative regulation of tyrosine phosphorylation of Stat6 protein
          glucose homeostasis
          negative regulation of macrophage differentiation
          positive regulation of gluconeogenesis
          negative regulation of insulin receptor signaling pathway
          negative regulation of inflammatory response
          negative regulation of T cell receptor signaling pathway
          negative regulation of chemotaxis
          regulation of interferon-gamma-mediated signaling pathway
          negative regulation of interferon-gamma-mediated signaling pathway
          negative regulation of type I interferon-mediated signaling pathway
          negative regulation of protein tyrosine kinase activity
          negative regulation of interleukin-6-mediated signaling pathway
          negative regulation of ERK1 and ERK2 cascade
          regulation of hepatocyte growth factor receptor signaling pathway
          negative regulation of interleukin-2-mediated signaling pathway
          negative regulation of prolactin signaling pathway
          negative regulation of interleukin-4-mediated signaling pathway
          negative regulation of macrophage colony-stimulating factor signaling pathway
          negative regulation of positive thymic T cell selection
          positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          positive regulation of PERK-mediated unfolded protein response
          negative regulation of platelet-derived growth factor receptor-beta signaling pathway
          protein tyrosine phosphatase activity
          non-membrane spanning protein tyrosine phosphatase activity
          integrin binding
          protein binding
          protein kinase binding
          syntaxin binding
          receptor tyrosine kinase binding

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