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          System Message

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          LOADING ...
          See other TLR3 SIRNA Assays ›
          Gene Symbol:
          TLR3
          Gene Name:
          toll like receptor 3
          Gene Aliases:
          CD283, IIAE2
          Chromosome Location:
          Chr.4: 186069155 - 186086724 on Build GRCh38
          UniGene ID:
          Hs.657724
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 4530

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: TLR3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_003265.2 NP_003256.1 2 327
          GenBank mRNA AB445631.1 - 1 226
          AK314208.1 - 2 326
          BC059372.1 - 2 326
          BC094737.1 - 2 326 30531515
          BC096333.1 - 2 304 40008349
          BC096334.3 - 2 304 40008350
          BC096335.1 - 2 304 40008351
          DA374150.1 - 2 327
          DQ445682.1 - 2 297
          U88879.1 - 2 299

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          toll-like receptor signaling pathway
          microglial cell activation involved in immune response
          regulation of dendritic cell cytokine production
          MyD88-independent toll-like receptor signaling pathway
          inflammatory response
          hyperosmotic response
          signal transduction
          I-kappaB kinase/NF-kappaB signaling
          activation of NF-kappaB-inducing kinase activity
          I-kappaB phosphorylation
          male gonad development
          detection of virus
          positive regulation of gene expression
          positive regulation of chemokine production
          positive regulation of interferon-beta production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-6 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          positive regulation of toll-like receptor signaling pathway
          negative regulation of MyD88-independent toll-like receptor signaling pathway
          toll-like receptor 3 signaling pathway
          positive regulation of type III interferon production
          cellular response to interferon-beta
          TRIF-dependent toll-like receptor signaling pathway
          cellular response to drug
          positive regulation of NF-kappaB import into nucleus
          defense response to bacterium
          positive regulation of apoptotic process
          response to exogenous dsRNA
          positive regulation of interferon-gamma biosynthetic process
          positive regulation of chemokine biosynthetic process
          innate immune response
          positive regulation of interferon-alpha biosynthetic process
          positive regulation of interferon-beta biosynthetic process
          negative regulation of osteoclast differentiation
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          positive regulation of inflammatory response
          positive regulation of NF-kappaB transcription factor activity
          defense response to virus
          necroptotic process
          cellular response to mechanical stimulus
          cellular response to interferon-gamma
          cellular response to exogenous dsRNA
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          necroptotic signaling pathway
          double-stranded RNA binding
          receptor activity
          transmembrane signaling receptor activity
          protein binding
          identical protein binding

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