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          System Message

          OKCancel
          LOADING ...
          See other DAB2 SIRNA Assays ›
          Gene Symbol:
          Dab2
          Gene Name:
          disabled 2, mitogen-responsive phosphoprotein
          Gene Aliases:
          Doc-2, Doc2
          Chromosome Location:
          Chr.2: 55747353 - 55768848 on Build Rnor_6.0
          UniGene ID:
          Rn.161784
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID 52773

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Dab2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_024159.1 NP_077073.1 1, 2 105
          GenBank mRNA AF045657.1 - 1, 2 95
          BC097314.1 - 1, 2 140 7444786
          FQ224185.1 - 415
          U95177.1 - 1, 2 105
          U95178.1 - 1, 2 105

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          More Information


          Panther Classification:

          Molecular Function -

          scaffold/adaptor protein

          Gene Ontology Categories:

          Function(s) Process(es)

          cell morphogenesis involved in differentiation
          in utero embryonic development
          positive regulation of receptor recycling
          positive regulation of protein phosphorylation
          endocytosis
          receptor-mediated endocytosis
          pinocytosis
          apoptotic process
          integrin-mediated signaling pathway
          activation of JUN kinase activity
          endoderm development
          excretion
          positive regulation of epithelial to mesenchymal transition
          positive regulation of pathway-restricted SMAD protein phosphorylation
          negative regulation of neuron projection development
          protein transport
          Wnt signaling pathway
          myeloid cell differentiation
          negative regulation of cell growth
          positive regulation of cell migration
          positive regulation of transforming growth factor beta receptor signaling pathway
          negative regulation of protein binding
          positive regulation of aldosterone biosynthetic process
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          positive regulation of transcription elongation from RNA polymerase II promoter
          leading edge cell differentiation
          negative regulation of apoptotic process
          positive regulation of cell adhesion
          positive regulation of endocytosis
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          clathrin coat assembly
          response to steroid hormone
          negative regulation of epithelial cell proliferation
          positive regulation of SMAD protein import into nucleus
          negative regulation of androgen receptor signaling pathway
          negative regulation of ERK1 and ERK2 cascade
          cellular response to epidermal growth factor stimulus
          cellular response to transforming growth factor beta stimulus
          negative regulation of canonical Wnt signaling pathway
          positive regulation of substrate adhesion-dependent cell spreading
          response to salt
          negative regulation of protein localization to plasma membrane
          positive regulation of Wnt signaling pathway, planar cell polarity pathway
          regulation of Rho-dependent protein serine/threonine kinase activity
          positive regulation of clathrin-mediated endocytosis
          positive regulation of early endosome to late endosome transport
          positive regulation of aldosterone secretion
          positive regulation of integrin-mediated signaling pathway
          negative regulation of extrinsic apoptotic signaling pathway
          integrin binding
          protein binding
          phosphatidylinositol-4,5-bisphosphate binding
          protein C-terminus binding
          clathrin binding
          phosphatidylinositol binding
          AP-2 adaptor complex binding
          clathrin adaptor activity
          cargo receptor activity
          SMAD binding

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