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          System Message

          OKCancel
          LOADING ...
          See other NR1H4 SIRNA Assays ›
          Gene Symbol:
          NR1H4
          Gene Name:
          nuclear receptor subfamily 1 group H member 4
          Gene Aliases:
          BAR, FXR, HRR-1, HRR1, RIP14
          Chromosome Location:
          Chr.12: 100473773 - 100563867 on Build GRCh38
          UniGene ID:
          Hs.282735
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 5450

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: NR1H4
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001206977.1 NP_001193906.1 5 957
          NM_001206978.1 NP_001193907.1 4 790
          NM_001206979.1 NP_001193908.1 4 790
          NM_001206992.1 NP_001193921.1 2 372
          NM_001206993.1 NP_001193922.1 2 372
          NM_005123.3 NP_005114.1 4 790
          NR_135146.1 4 790
          XM_006719719.2 XP_006719782.1 2 373
          XM_011539040.2 XP_011537342.1 4 1708
          XM_011539041.2 XP_011537343.1 2 770
          XM_011539042.1 XP_011537344.1 2 373
          GenBank mRNA AB307699.1 - 2 314
          AF384555.1 - 2 314
          AF478445.1 - 2 372
          AF478446.1 - 2 372
          AK296612.1 - 2 373
          AK296647.1 - 2 308
          AK312959.1 - 4 791
          BC071778.1 - 2 312
          BC130573.1 - 4 647 40146604
          BC144183.1 - 4 647
          BC144184.1 - 4 647 9052704
          BX571749.1 - 2 369
          HQ709175.1 - 2 314
          U68233.1 - 4 667

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          nitrogen catabolite activation of transcription from RNA polymerase II promoter
          regulation of carbohydrate metabolic process
          transcription initiation from RNA polymerase II promoter
          inflammatory response
          signal transduction
          Notch signaling pathway
          bile acid metabolic process
          response to glucose
          regulation of low-density lipoprotein particle clearance
          bile acid and bile salt transport
          intracellular receptor signaling pathway
          response to lipopolysaccharide
          toll-like receptor 4 signaling pathway
          regulation of urea metabolic process
          histone H3-R17 methylation
          cellular triglyceride homeostasis
          bile acid signaling pathway
          intracellular bile acid receptor signaling pathway
          negative regulation of apoptotic process
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          steroid hormone mediated signaling pathway
          innate immune response
          positive regulation of transcription from RNA polymerase II promoter
          digestive tract development
          regulation of insulin secretion involved in cellular response to glucose stimulus
          regulation of bile acid biosynthetic process
          negative regulation of bile acid biosynthetic process
          cellular response to fatty acid
          cellular response to organonitrogen compound
          interleukin-17 secretion
          regulation of cholesterol metabolic process
          negative regulation of interferon-gamma secretion
          negative regulation of tumor necrosis factor secretion
          positive regulation of glutamate metabolic process
          positive regulation of ammonia assimilation cycle
          RNA polymerase II distal enhancer sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcriptional activator activity, RNA polymerase II transcription factor binding
          transcription factor activity, sequence-specific DNA binding
          transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
          steroid hormone receptor activity
          transcription coactivator activity
          transcription corepressor activity
          RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
          thyroid hormone receptor activity
          protein binding
          zinc ion binding
          ligand-dependent nuclear receptor binding
          bile acid binding
          bile acid receptor activity
          peptide binding
          sequence-specific DNA binding
          retinoid X receptor binding
          chenodeoxycholic acid binding

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