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          System Message

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          LOADING ...
          See other XBP1 SIRNA Assays ›
          Gene Symbol:
          XBP1
          Gene Name:
          X-box binding protein 1
          Gene Aliases:
          TREB-5, TREB5, XBP-1, XBP2
          Chromosome Location:
          Chr.22: 28794560 - 28800572 on Build GRCh38
          UniGene ID:
          Hs.437638
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 5533

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: XBP1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001079539.1 NP_001073007.1 6 1750
          NM_005080.3 NP_005071.2 5 1776
          GenBank mRNA AB076383.1 - 5 1736
          AB076384.1 - 6 1710
          AK093842.1 - 2 2128
          BC000938.1 - 5 1733 3449394
          BC012841.1 - 5 1760 3856898
          BC015709.1 - 5 1669
          M31627.1 - 5 1748

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001271731, NM_001004210, FQ230367, FQ232289, FQ225483, and others.
          This siRNA also targets the following transcripts in Mouse: NM_001271730, NM_013842, AF027963, AK205453, AF443192, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          angiogenesis
          liver development
          endothelial cell proliferation
          positive regulation of immunoglobulin production
          transcription from RNA polymerase II promoter
          ubiquitin-dependent protein catabolic process
          fatty acid biosynthetic process
          autophagy
          immune response
          positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
          muscle organ development
          regulation of autophagy
          negative regulation of myotube differentiation
          protein transport
          endoplasmic reticulum unfolded protein response
          exocrine pancreas development
          protein destabilization
          cellular response to nutrient
          cellular response to insulin stimulus
          cellular triglyceride homeostasis
          IRE1-mediated unfolded protein response
          ATF6-mediated unfolded protein response
          cellular response to glucose starvation
          cholesterol homeostasis
          negative regulation of apoptotic process
          positive regulation of MHC class II biosynthetic process
          positive regulation of B cell differentiation
          positive regulation of T cell differentiation
          positive regulation of fat cell differentiation
          positive regulation of transcription from RNA polymerase II promoter
          neuron development
          positive regulation of immunoglobulin secretion
          fatty acid homeostasis
          sterol homeostasis
          adipose tissue development
          epithelial cell maturation involved in salivary gland development
          intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
          cellular response to lipopolysaccharide
          cellular response to amino acid stimulus
          cellular response to fructose stimulus
          cellular response to glucose stimulus
          cellular response to interleukin-4
          cellular response to peptide hormone stimulus
          positive regulation of plasma cell differentiation
          positive regulation of endoplasmic reticulum unfolded protein response
          positive regulation of proteasomal protein catabolic process
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          positive regulation of lactation
          response to insulin-like growth factor stimulus
          positive regulation of hepatocyte proliferation
          positive regulation of interleukin-6 secretion
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          core promoter binding
          RNA polymerase II transcription factor binding
          enhancer sequence-specific DNA binding
          DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          phosphatidylinositol 3-kinase regulatory subunit binding
          histone deacetylase binding
          protein heterodimerization activity

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