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          System Message

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          LOADING ...
          See other SMAD4 SIRNA Assays ›
          Gene Symbol:
          SMAD4
          Gene Name:
          SMAD family member 4
          Gene Aliases:
          DPC4, JIP, MADH4, MYHRS
          Chromosome Location:
          Chr.18: 51030213 - 51085042 on Build GRCh38
          UniGene ID:
          Hs.75862
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 5540

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: SMAD4
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_005359.5 NP_005350.1 12 3019
          GenBank mRNA BC002379.2 - 13 2714 2961238
          BX647129.1 - 8 4483
          U44378.1 - 11 2608

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          More Information


          Panther Classification:

          Molecular Function -

          DNA-binding transcription factor gene-specific transcriptional regulator

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          ovarian follicle development
          branching involved in ureteric bud morphogenesis
          response to hypoxia
          in utero embryonic development
          gastrulation with mouth forming second
          atrioventricular valve formation
          epithelial to mesenchymal transition involved in endocardial cushion formation
          left ventricular cardiac muscle tissue morphogenesis
          positive regulation of cell proliferation involved in heart valve morphogenesis
          brainstem development
          transcription from RNA polymerase II promoter
          cellular iron ion homeostasis
          transforming growth factor beta receptor signaling pathway
          SMAD protein complex assembly
          spermatogenesis
          single fertilization
          axon guidance
          endoderm development
          mesoderm development
          cell proliferation
          negative regulation of cell proliferation
          negative regulation of cardiac muscle hypertrophy
          positive regulation of epithelial to mesenchymal transition
          positive regulation of pathway-restricted SMAD protein phosphorylation
          neural crest cell differentiation
          regulation of transforming growth factor beta receptor signaling pathway
          negative regulation of cell growth
          BMP signaling pathway
          positive regulation of transforming growth factor beta receptor signaling pathway
          positive regulation of BMP signaling pathway
          somite rostral/caudal axis specification
          regulation of transforming growth factor beta2 production
          positive regulation of luteinizing hormone secretion
          somatic stem cell population maintenance
          intracellular signal transduction
          atrioventricular canal development
          endothelial cell activation
          embryonic digit morphogenesis
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of follicle-stimulating hormone secretion
          developmental growth
          neuron fate commitment
          sebaceous gland development
          formation of anatomical boundary
          regulation of binding
          positive regulation of histone H3-K4 methylation
          regulation of hair follicle development
          palate development
          uterus development
          positive regulation of SMAD protein import into nucleus
          SMAD protein signal transduction
          ventricular septum morphogenesis
          negative regulation of cell death
          endocardial cell differentiation
          female gonad morphogenesis
          interleukin-6-mediated signaling pathway
          negative regulation of ERK1 and ERK2 cascade
          response to transforming growth factor beta
          cellular response to BMP stimulus
          metanephric mesenchyme morphogenesis
          nephrogenic mesenchyme morphogenesis
          seminiferous tubule development
          positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
          positive regulation of histone H3-K9 acetylation
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          core promoter proximal region sequence-specific DNA binding
          transcription factor activity, protein binding
          transcription factor activity, RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          RNA polymerase II transcription factor binding
          DNA binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          collagen binding
          transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
          identical protein binding
          protein homodimerization activity
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          metal ion binding
          protein heterodimerization activity
          I-SMAD binding
          R-SMAD binding

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          Host server : magellan-search-green-55658555d6-7l2qm:80/100.66.75.127:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline