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          System Message

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          LOADING ...
          See other EIF2AK3 SIRNA Assays ›
          Gene Symbol:
          EIF2AK3
          Gene Name:
          eukaryotic translation initiation factor 2 alpha kinase 3
          Gene Aliases:
          PEK, PERK, WRS
          Chromosome Location:
          Chr.2: 88556740 - 88627576 on Build GRCh38
          UniGene ID:
          Hs.591589
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 592

          Purification
          Size
          Availability Inventoried
          Catalog # AM51331
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: EIF2AK3
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001313915.1 NP_001300844.1 2, 3 322
          NM_004836.6 NP_004827.4 2, 3 748
          XM_017005376.1 XP_016860865.1 2, 3 444
          GenBank mRNA AF110146.1 - 2, 3 515
          AF193339.1 - 2, 3 745
          AK128659.1 - 3, 4 501
          AK315287.1 - 2, 3 653
          BC126354.1 - 2, 3 542 8992070
          BC126356.1 - 2, 3 539 8992072
          CN285475.1 - 1, 2 75
          CR749382.1 - 2, 3 323
          DB287944.1 - 2, 3 541

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          More Information


          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          skeletal system development
          ossification
          angiogenesis
          chondrocyte development
          protein phosphorylation
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          ER overload response
          endoplasmic reticulum organization
          positive regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          regulation of translational initiation by eIF2 alpha phosphorylation
          negative regulation of translation
          peptidyl-serine phosphorylation
          calcium-mediated signaling
          insulin secretion
          bone mineralization
          endoplasmic reticulum unfolded protein response
          endocrine pancreas development
          negative regulation of myelination
          negative regulation of translational initiation in response to stress
          cellular response to amino acid starvation
          response to endoplasmic reticulum stress
          eiF2alpha phosphorylation in response to endoplasmic reticulum stress
          PERK-mediated unfolded protein response
          cellular response to glucose starvation
          positive regulation of transcription from RNA polymerase I promoter
          protein autophosphorylation
          insulin-like growth factor receptor signaling pathway
          protein homooligomerization
          regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
          cellular response to cold
          positive regulation of protein localization to nucleus
          regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          response to manganese-induced endoplasmic reticulum stress
          protein kinase activity
          protein serine/threonine kinase activity
          eukaryotic translation initiation factor 2alpha kinase activity
          protein binding
          ATP binding
          enzyme binding
          protein phosphatase binding
          identical protein binding
          protein homodimerization activity
          Hsp90 protein binding

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          Host server : magellan-search-blue-55ff9ddd88-gh6bl:80/100.66.76.225:80.
          git-commit: d366ff9721d93504b2ac26a183b2b3e3d0e7d9ec
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.42.0-2026.01.03-1.0