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          System Message

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          LOADING ...
          See other PAX6 SIRNA Assays ›
          Gene Symbol:
          Pax6
          Gene Name:
          paired box 6
          Gene Aliases:
          1500038E17Rik, AEY11, Dey, Gsfaey11, Pax-6, Sey
          Chromosome Location:
          Chr.2: 105667518 - 105697364 on Build GRCm38
          UniGene ID:
          Mm.33870
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 71258

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Pax6
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001244198.1 NP_001231127.1 6 511
          NM_001244200.1 NP_001231129.1 7 723
          NM_001244201.1 NP_001231130.1 5 469
          NM_001244202.1 NP_001231131.1 5 1025
          NM_013627.5 NP_038655.1 6 1067
          GenBank mRNA AF443223.1 - 2 184
          AJ292077.1 - 5 328
          AJ307468.1 - 5 335
          AK028059.1 - 5 470
          AK032616.1 - 6 512
          AK045805.1 - 5 1026
          BC011272.1 - 6 755 4008490
          BC036957.1 - 5 465 4504106
          M77842.1 - 1 54
          X63963.1 - 6 388

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Human: NM_001258463, NM_001604, NM_000280, NM_001258465, NM_001127612, and others.
          This siRNA also targets the following transcripts in Rat: NM_013001, XM_006234634, XM_008762060, XM_006234633, XM_006234636, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          establishment of mitotic spindle orientation
          blood vessel development
          cell fate determination
          neural crest cell migration
          neuron migration
          negative regulation of protein phosphorylation
          positive regulation of neuroblast proliferation
          epithelial cell development
          lens development in camera-type eye
          type B pancreatic cell differentiation
          pancreatic A cell differentiation
          pancreatic A cell development
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          smoothened signaling pathway
          multicellular organism development
          axonogenesis
          axon guidance
          brain development
          salivary gland morphogenesis
          negative regulation of cell proliferation
          regulation of asymmetric cell division
          dorsal/ventral axis specification
          anterior/posterior pattern specification
          dorsal/ventral pattern formation
          regulation of gene expression
          positive regulation of gene expression
          regulation of neuron projection development
          pallium development
          rhombomere morphogenesis
          olfactory bulb development
          oligodendrocyte cell fate specification
          cerebral cortex regionalization
          forebrain anterior/posterior pattern specification
          forebrain dorsal/ventral pattern formation
          commitment of neuronal cell to specific neuron type in forebrain
          forebrain-midbrain boundary formation
          regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
          regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
          regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment
          telencephalon regionalization
          pituitary gland development
          interkinetic nuclear migration
          signal transduction involved in regulation of gene expression
          cell differentiation
          keratinocyte differentiation
          regulation of cell migration
          positive regulation of epithelial cell differentiation
          forebrain development
          hindbrain development
          lacrimal gland development
          protein localization to organelle
          eye photoreceptor cell development
          glucose homeostasis
          positive regulation of cell fate specification
          camera-type eye development
          cell fate commitment
          regulation of neuron differentiation
          negative regulation of neuron differentiation
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          regulation of timing of cell differentiation
          embryonic camera-type eye morphogenesis
          astrocyte differentiation
          negative regulation of epithelial cell proliferation
          regulation of neurogenesis
          retina development in camera-type eye
          iris morphogenesis
          cornea development in camera-type eye
          neural precursor cell proliferation
          positive regulation of glucagon secretion
          insulin metabolic process
          negative regulation of neural precursor cell proliferation
          positive regulation of neuron migration
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          RNA polymerase II core promoter sequence-specific DNA binding
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          DNA binding
          AT DNA binding
          chromatin binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          transcription factor binding
          protein kinase binding
          ubiquitin protein ligase binding
          histone acetyltransferase binding
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          co-SMAD binding
          R-SMAD binding
          HMG box domain binding

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          Host server : magellan-search-green-55658555d6-b5kzb:80/100.66.79.83:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline