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          System Message

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          LOADING ...
          See other AKT1 SIRNA Assays ›
          Gene Symbol:
          AKT1
          Gene Name:
          AKT serine/threonine kinase 1
          Gene Aliases:
          AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
          Chromosome Location:
          Chr.14: 104769349 - 104795743 on Build GRCh38
          UniGene ID:
          Hs.525622
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS100346
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: AKT1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001014431.1 NP_001014431.1 2 357
          NM_001014432.1 NP_001014432.1 3 441
          NM_005163.2 NP_005154.2 2 571
          XM_005267401.1 XP_005267458.1 2 506
          XM_017021075.1 XP_016876564.1 3 684
          XM_017021076.1 XP_016876565.1 3 590
          XM_017021077.1 XP_016876566.1 2 506
          XM_017021078.1 XP_016876567.1 3 217
          GenBank mRNA AB451242.1 - 1 17
          AB451367.1 - 1 17
          AK122894.1 - 2 1498
          AK314256.1 - 2 170
          BC000479.2 - 2 292 2964603
          BC063408.1 - 127
          BC084538.1 - 3 435 6645486
          BX648205.1 - 1 975
          KF836747.1 - 3 335
          KF836748.1 - 3 310
          KF836750.1 - 2 157
          KU177898.1 - 1 17
          KU177899.1 - 1 17
          M63167.1 - 2 215

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          More Information


          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          protein import into nucleus, translocation
          osteoblast differentiation
          maternal placenta development
          positive regulation of protein phosphorylation
          positive regulation of endothelial cell proliferation
          glycogen biosynthetic process
          regulation of glycogen biosynthetic process
          glucose metabolic process
          translation
          regulation of translation
          cellular protein modification process
          protein phosphorylation
          negative regulation of protein kinase activity
          nitric oxide biosynthetic process
          activation-induced cell death of T cells
          inflammatory response
          cellular response to DNA damage stimulus
          response to oxidative stress
          signal transduction
          G-protein coupled receptor signaling pathway
          germ cell development
          aging
          cell proliferation
          insulin receptor signaling pathway
          apoptotic mitochondrial changes
          response to heat
          negative regulation of autophagy
          negative regulation of gene expression
          negative regulation of plasma membrane long-chain fatty acid transport
          positive regulation of fibroblast migration
          positive regulation of sodium ion transport
          positive regulation of glucose metabolic process
          negative regulation of endopeptidase activity
          regulation of neuron projection development
          regulation of phosphatidylinositol 3-kinase signaling
          glucose transport
          phosphorylation
          protein ubiquitination
          peptidyl-serine phosphorylation
          peptidyl-threonine phosphorylation
          spinal cord development
          cell projection organization
          cell differentiation
          protein catabolic process
          platelet activation
          hyaluronan metabolic process
          positive regulation of cell growth
          regulation of cell migration
          endocrine pancreas development
          T cell costimulation
          regulation of myelination
          positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
          lipopolysaccharide-mediated signaling pathway
          negative regulation of fatty acid beta-oxidation
          positive regulation of endodeoxyribonuclease activity
          response to food
          positive regulation of cellular protein metabolic process
          peripheral nervous system myelin maintenance
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          cellular response to insulin stimulus
          positive regulation of peptidyl-serine phosphorylation
          response to fluid shear stress
          intracellular signal transduction
          cellular response to vascular endothelial growth factor stimulus
          ERBB2 signaling pathway
          glucose homeostasis
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
          regulation of mRNA stability
          protein kinase B signaling
          positive regulation of blood vessel endothelial cell migration
          positive regulation of nitric oxide biosynthetic process
          positive regulation of fat cell differentiation
          positive regulation of glycogen biosynthetic process
          positive regulation of epidermal growth factor receptor signaling pathway
          negative regulation of cell size
          negative regulation of proteolysis
          positive regulation of vasoconstriction
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of glucose import
          negative regulation of JNK cascade
          protein autophosphorylation
          positive regulation of lipid biosynthetic process
          insulin-like growth factor receptor signaling pathway
          phosphatidylinositol-mediated signaling
          regulation of nitric-oxide synthase activity
          positive regulation of nitric-oxide synthase activity
          positive regulation of sequence-specific DNA binding transcription factor activity
          striated muscle cell differentiation
          response to growth hormone
          mammary gland epithelial cell differentiation
          glycogen cell differentiation involved in embryonic placenta development
          labyrinthine layer blood vessel development
          response to UV-A
          cellular response to mechanical stimulus
          cellular response to epidermal growth factor stimulus
          cellular response to prostaglandin E stimulus
          cellular response to organic cyclic compound
          cellular response to hypoxia
          establishment of protein localization to mitochondrion
          maintenance of protein location in mitochondrion
          positive regulation of establishment of protein localization to plasma membrane
          negative regulation of release of cytochrome c from mitochondria
          cellular response to granulocyte macrophage colony-stimulating factor stimulus
          execution phase of apoptosis
          chemical synaptic transmission, postsynaptic
          negative regulation of protein kinase activity by protein phosphorylation
          positive regulation of protein localization to nucleus
          negative regulation of neuron death
          regulation of signal transduction by p53 class mediator
          regulation of cell cycle checkpoint
          negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
          cellular response to nerve growth factor stimulus
          response to insulin-like growth factor stimulus
          negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
          protein kinase activity
          protein serine/threonine kinase activity
          protein serine/threonine/tyrosine kinase activity
          protein kinase C binding
          protein binding
          ATP binding
          phosphatidylinositol-3,4,5-trisphosphate binding
          kinase activity
          enzyme binding
          nitric-oxide synthase regulator activity
          GTPase activating protein binding
          identical protein binding
          phosphatidylinositol-3,4-bisphosphate binding
          protein phosphatase 2A binding
          14-3-3 protein binding

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