Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign In
Don't have an account ? Create Account
  • Applications
    • Real-Time PCR
    • Oligos, Primers, Probes and Genes
    • Cloning
    • Protein Biology
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Cell Analysis
    • Mass Spectrometry
    • Chromatography
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Online Order
    • Custom Primers & TaqMan Probes
    • miRNA Mimics & Inhibitors
    • Stealth RNAi / siRNA
    • Silencer Select siRNAs
    • Custom DNA Oligos
    • GeneArt Services
    • GeneArt Strings DNA Fragments
    • TrueGuide CRISPR gRNA
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • See all online orderable products
  • Services
    • Custom Services
    • Instrument Qualification Services
    • Technical Services
    • Enterprise Services
    • Pipette Services
    • Sample Request
    • Instrument Maintenance Services
    • Repairs and Relocation Services
    • OEM and Licensing Services
    • Events, Seminars, Training
    • See all services
  • Support
    • Catalogs
    • Application Notes
    • Safety Data Sheets
    • Legal and Regulatory
    • Certificates of Analysis Search
    • Nunc/Nalgene Product Certificates
    • e-learning
    • FAQs
    • Learning Centers
    • Technical Support Centers
    • See all help and support topics
  • Contact Us
  • Quick Order
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • Contact Us
          • Quick Order
          • Sign In
            Sign In
            Don't have an account ? Create Account
            • Connect Your Lab
            • Custom Products & Projects
            • Instrument Management
          This product has been added to your favorites list. Go to My Favorites

          System Message

          OKCancel
          LOADING ...
          See other TLR4 SIRNA Assays ›
          Gene Symbol:
          TLR4
          Gene Name:
          toll like receptor 4
          Gene Aliases:
          ARMD10, CD284, TLR-4, TOLL
          Chromosome Location:
          Chr.9: 117704175 - 117717491 on Build GRCh38
          UniGene ID:
          Hs.174312
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS110820
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price Contact Us
          Your Price
          Online offer:
          3062.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

          LOADING...
          ×
          Back To Top

          siRNA Details

          Gene Symbol: TLR4
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_003266.3 NP_003257.1 4 725
          NM_138554.4 NP_612564.1 3 605
          NM_138557.2 NP_612567.1 2 438
          GenBank mRNA AB445638.1 - 3 307
          AK226155.1 - 4 480
          AK290053.1 - 4 708
          AK293068.1 - 3 436
          AK303730.1 - 2 269
          AL710219.1 - 4 575
          BC025294.1 - 2 224
          BC117422.1 - 3 327 40125973
          BC143841.1 - 4 447
          DA187988.1 - 2 438
          U88880.1 - 4 471
          U93091.1 - 3 410

          Back To Top

          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          toll-like receptor signaling pathway
          B cell proliferation involved in immune response
          nitric oxide production involved in inflammatory response
          regulation of dendritic cell cytokine production
          MyD88-dependent toll-like receptor signaling pathway
          MyD88-independent toll-like receptor signaling pathway
          inflammatory response
          immune response
          I-kappaB kinase/NF-kappaB signaling
          I-kappaB phosphorylation
          positive regulation of platelet activation
          positive regulation of gene expression
          astrocyte development
          detection of fungus
          positive regulation of B cell proliferation
          lipopolysaccharide-mediated signaling pathway
          response to lipopolysaccharide
          detection of lipopolysaccharide
          interferon-gamma production
          negative regulation of interferon-gamma production
          negative regulation of interleukin-17 production
          negative regulation of interleukin-23 production
          negative regulation of interleukin-6 production
          negative regulation of tumor necrosis factor production
          positive regulation of chemokine production
          positive regulation of interferon-alpha production
          positive regulation of interferon-beta production
          positive regulation of interferon-gamma production
          positive regulation of interleukin-1 production
          positive regulation of interleukin-10 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-6 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          negative regulation of MyD88-independent toll-like receptor signaling pathway
          toll-like receptor 4 signaling pathway
          TRIF-dependent toll-like receptor signaling pathway
          T-helper 1 type immune response
          macrophage activation
          positive regulation of NF-kappaB import into nucleus
          positive regulation of tumor necrosis factor biosynthetic process
          defense response to bacterium
          positive regulation of interleukin-12 biosynthetic process
          innate immune response
          positive regulation of MHC class II biosynthetic process
          positive regulation of interferon-beta biosynthetic process
          positive regulation of interleukin-8 biosynthetic process
          positive regulation of nitric oxide biosynthetic process
          negative regulation of osteoclast differentiation
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          interleukin-1 beta secretion
          regulation of cytokine secretion
          positive regulation of inflammatory response
          defense response to Gram-negative bacterium
          positive regulation of NF-kappaB transcription factor activity
          positive regulation of nitric-oxide synthase biosynthetic process
          intestinal epithelial structure maintenance
          positive regulation of macrophage cytokine production
          necroptotic process
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
          positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
          cellular response to lipopolysaccharide
          cellular response to lipoteichoic acid
          cellular response to mechanical stimulus
          apoptotic signaling pathway
          positive regulation of NLRP3 inflammasome complex assembly
          lipopolysaccharide binding
          lipopolysaccharide receptor activity
          receptor activity
          transmembrane signaling receptor activity
          protein binding

          Back To Top

          Related Products

          • Anti-GAPDH, Mouse Monoclonal 6C5
          • Anti-β-Actin, Mouse Monoclonal AC-15
          • TaqMan® Gene Expression Cells-to-CT™
          • Neon™ Transfection System 100 µL Kit
          • Lipofectamine™ RNAiMAX Transfection Reagent
          • Invivofectamine 2.0
          • Lipofectamine™ 2000 Transfection Reagent
          • Neon™ Transfection System
          Ordering Plus Icon Minus Icon
          • Online Orderable Products
          • Privacy Policy for Online Ordering
          • Act on Specified Commercial Transactions
          • About Returns
          • About Displayed Prices
          • About Shipping Fees
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Study information disclosure
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Seminars
          • Blog
          About Thermo Fisher Plus Icon Minus Icon
          • Corporate Information
          • Social Responsibility (CSR)
          • Enhancing Customer Experience
          • Careers Careers
          • News
          • Trademarks
          • Policies and Notices
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          Japan flag icon
          Japan

          Your items have has been added!


          Host server : magellan-search-green-55658555d6-pnd5g:80/100.66.79.83:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline