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          System Message

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          LOADING ...
          See other PCSK9 SIRNA Assays ›
          Gene Symbol:
          PCSK9
          Gene Name:
          proprotein convertase subtilisin/kexin type 9
          Gene Aliases:
          FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9
          Chromosome Location:
          Chr.1: 55039476 - 55064853 on Build GRCh38
          UniGene ID:
          Hs.18844
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS153993
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price Contact Us
          Your Price
          Online offer:
          3062.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PCSK9
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_174936.3 NP_777596.2 5, 6 1159
          NR_110451.1 3, 4 456
          GenBank mRNA AK075365.1 - 5, 6 1088
          AK122717.1 - 6, 7 844
          AK124635.1 - 2, 3 1618
          AK297473.1 - 3, 4 456
          EF692496.1 - 5, 6 797

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_199253, AY847775, BC133063.
          This siRNA also targets the following transcripts in Mouse: NM_153565, BC038085, AK043077, AK149520, AY273821.

          Panther Classification:

          Molecular Function -

          serine protease

          Gene Ontology Categories:

          Function(s) Process(es)

          kidney development
          liver development
          negative regulation of receptor recycling
          positive regulation of receptor internalization
          triglyceride metabolic process
          phospholipid metabolic process
          apoptotic process
          lysosomal transport
          cholesterol metabolic process
          cellular response to starvation
          regulation of receptor activity
          negative regulation of low-density lipoprotein particle clearance
          protein autoprocessing
          neurogenesis
          neuron differentiation
          low-density lipoprotein particle receptor catabolic process
          positive regulation of low-density lipoprotein particle receptor catabolic process
          cellular response to insulin stimulus
          lipoprotein metabolic process
          cholesterol homeostasis
          regulation of neuron apoptotic process
          positive regulation of neuron apoptotic process
          negative regulation of receptor activity
          negative regulation of sodium ion transmembrane transporter activity
          serine-type endopeptidase activity
          protein binding
          sodium channel inhibitor activity
          low-density lipoprotein particle binding
          receptor inhibitor activity
          apolipoprotein binding
          very-low-density lipoprotein particle binding
          apolipoprotein receptor binding
          protein self-association
          poly(A) RNA binding
          low-density lipoprotein particle receptor binding
          very-low-density lipoprotein particle receptor binding

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          Host server : magellan-search-green-55658555d6-72rkq:80/100.66.79.224:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline