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          System Message

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          LOADING ...
          See other LRP6 SIRNA Assays ›
          Gene Symbol:
          LRP6
          Gene Name:
          LDL receptor related protein 6
          Gene Aliases:
          ADCAD2, STHAG7
          Chromosome Location:
          Chr.12: 12116025 - 12267021 on Build GRCh38
          UniGene ID:
          Hs.584775
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS180911
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price Contact Us
          Your Price
          Online offer:
          3062.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: LRP6
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_002336.2 NP_002327.2 6, 7 1512
          XM_006719078.3 XP_006719141.1 6, 7 1656
          XM_011520671.2 XP_011518973.1 5, 6 1262
          XM_017019304.1 XP_016874793.1 4, 5 1330
          GenBank mRNA AB209683.1 - 5, 6 964
          AF074264.1 - 6, 7 1447
          BC117136.1 - 6, 7 1404 40125687
          BC126405.1 - 6, 7 1404 8992121
          BC143725.1 - 6, 7 1404 9052239

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_008514, AF074265, BC060704.

          Panther Classification:

          Molecular Function -

          apolipoprotein

          Gene Ontology Categories:

          Function(s) Process(es)

          neural tube closure
          negative regulation of protein phosphorylation
          pericardium morphogenesis
          negative regulation of protein kinase activity
          positive regulation of cytosolic calcium ion concentration
          chemical synaptic transmission
          embryonic pattern specification
          neural crest formation
          neural crest cell differentiation
          Wnt signaling pathway
          single organismal cell-cell adhesion
          cerebellum morphogenesis
          thalamus development
          cerebral cortex development
          midbrain-hindbrain boundary development
          negative regulation of smooth muscle cell apoptotic process
          external genitalia morphogenesis
          odontogenesis of dentin-containing tooth
          response to peptide hormone
          Wnt signaling pathway involved in dorsal/ventral axis specification
          canonical Wnt signaling pathway involved in neural crest cell differentiation
          canonical Wnt signaling pathway involved in regulation of cell proliferation
          positive regulation of cell cycle
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of sequence-specific DNA binding transcription factor activity
          palate development
          convergent extension
          embryonic retina morphogenesis in camera-type eye
          canonical Wnt signaling pathway
          face morphogenesis
          trachea cartilage morphogenesis
          cellular response to cholesterol
          dopaminergic neuron differentiation
          negative regulation of protein serine/threonine kinase activity
          protein localization to plasma membrane
          primitive streak formation
          negative regulation of canonical Wnt signaling pathway
          receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
          Wnt signaling pathway involved in somitogenesis
          axis elongation involved in somitogenesis
          positive regulation of canonical Wnt signaling pathway
          toxin transport
          beta-catenin destruction complex disassembly
          midbrain dopaminergic neuron differentiation
          Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
          positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
          low-density lipoprotein receptor activity
          receptor binding
          frizzled binding
          protein binding
          Wnt-protein binding
          kinase inhibitor activity
          toxin transporter activity
          apolipoprotein binding
          identical protein binding
          protein homodimerization activity
          Wnt-activated receptor activity
          coreceptor activity involved in Wnt signaling pathway
          coreceptor activity involved in canonical Wnt signaling pathway

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          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
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