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LOADING
See other SNCA SIRNA Assays ›
Gene Symbol:
SNCA
Gene Name:
synuclein alpha
Gene Aliases:
NACP, PARK1, PARK4, PD1
Chromosome Location:
Chr.4: 89724099 - 89838324 on Build GRCh38
UniGene ID:
Hs.21374
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID
HSS186008
Size
20 nmol
20 nmol
Availability
Made To Order
Catalog #
1299001
Price
Your Price
Online offer:
Check your price ›
Warenkorb
Genomic Map
siRNA Details
More Information
Genomic Map
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siRNA Details
Gene Symbol: SNCA
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_000345.3
NP_000336.1
4
447
NM_001146054.1
NP_001139526.1
4
443
NM_001146055.1
NP_001139527.1
4
254
NM_007308.2
NP_009292.1
4
443
XM_011532203.1
XP_011530505.1
4
476
XM_011532204.2
XP_011530506.1
4
580
XM_011532205.2
XP_011530507.1
4
282
XM_011532206.1
XP_011530508.1
4
304
XM_011532207.1
XP_011530509.1
4
291
XM_011532208.2
XP_011530510.1
4
324
XM_017008562.1
XP_016864051.1
4
318
XM_017008563.1
XP_016864052.1
4
344
GenBank mRNA
AK290169.1
-
4
268
AY049786.1
-
3
186
BC013293.2
-
4
607
3604532
BC108275.1
-
4
401
6147966
CR457058.1
-
3
184
CR736451.1
-
4
443
D31839.1
-
3
197
DA391115.1
-
4
254
HQ830267.1
-
4
456
HQ830268.1
-
4
619
HQ830269.1
-
4
309
JN709859.1
-
3
401
JN709860.1
-
3
401
JN709861.1
-
4
447
JN709862.1
-
3
405
JN709863.1
-
3
405
JN709864.1
-
4
254
JN709865.1
-
3
212
JN709866.1
-
3
212
JN709867.1
-
4
296
JN709868.1
-
3
254
JN709869.1
-
3
254
L08850.1
-
4
236
L36674.1
-
2
160
L36675.1
-
3
202
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More Information
Other Species Targeted
This siRNA also targets the following transcripts in Rat: S73008, AY550006, AF007758, S73007, AY550005.
This siRNA also targets the following transcripts in Mouse: NM_009221, NM_001042451, AK014472, BC046764, AF033261, and others.
Panther Classification:
Molecular Function -
membrane trafficking regulatory protein
Gene Ontology Categories:
Function(s)
Process(es)
negative regulation of transcription from RNA polymerase II promoter
microglial cell activation
positive regulation of receptor recycling
negative regulation of protein phosphorylation
positive regulation of neurotransmitter secretion
fatty acid metabolic process
neutral lipid metabolic process
phospholipid metabolic process
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
mitochondrial membrane organization
aging
adult locomotory behavior
response to iron(II) ion
regulation of phospholipase activity
negative regulation of platelet-derived growth factor receptor signaling pathway
regulation of glutamate secretion
regulation of dopamine secretion
negative regulation of microtubule polymerization
receptor internalization
protein destabilization
response to magnesium ion
negative regulation of transporter activity
response to lipopolysaccharide
negative regulation of monooxygenase activity
positive regulation of peptidyl-serine phosphorylation
response to interferon-gamma
cellular response to oxidative stress
negative regulation of histone acetylation
regulation of locomotion
dopamine biosynthetic process
response to drug
mitochondrial ATP synthesis coupled electron transport
regulation of macrophage activation
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
extracellular fibril organization
negative regulation of neuron apoptotic process
cellular protein metabolic process
cellular response to fibroblast growth factor stimulus
positive regulation of endocytosis
negative regulation of exocytosis
negative regulation of dopamine metabolic process
behavioral response to cocaine
regulation of long-term neuronal synaptic plasticity
synaptic vesicle endocytosis
synapse organization
regulation of acyl-CoA biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
dopamine uptake involved in synaptic transmission
negative regulation of dopamine uptake involved in synaptic transmission
negative regulation of serotonin uptake
negative regulation of norepinephrine uptake
calcium ion homeostasis
oxidation-reduction process
excitatory postsynaptic potential
long-term synaptic potentiation
positive regulation of inositol phosphate biosynthetic process
negative regulation of thrombin receptor signaling pathway
response to interleukin-1
cellular response to copper ion
cellular response to epinephrine stimulus
positive regulation of protein serine/threonine kinase activity
negative regulation of neuron death
negative regulation of mitochondrial electron transport, NADH to ubiquinone
positive regulation of glutathione peroxidase activity
positive regulation of hydrogen peroxide catabolic process
regulation of synaptic vesicle recycling
regulation of reactive oxygen species biosynthetic process
negative regulation of chaperone-mediated autophagy
magnesium ion binding
fatty acid binding
copper ion binding
calcium ion binding
protein binding
phospholipid binding
microtubule binding
ferrous iron binding
zinc ion binding
oxidoreductase activity
kinesin binding
protein domain specific binding
histone binding
identical protein binding
alpha-tubulin binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
phospholipase binding
transcription regulatory region DNA binding
dynein binding
protein N-terminus binding
tau protein binding
beta-tubulin binding
phosphoprotein binding
phospholipase D inhibitor activity
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