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          System Message

          OKCancel
          LOADING ...
          See other ASCL1 SIRNA Assays ›
          Gene Symbol:
          Ascl1
          Gene Name:
          achaete-scute complex homolog 1 (Drosophila)
          Gene Aliases:
          AI225900, ASH1, Mash1, bHLHa46
          Chromosome Location:
          Chr.10: 87491041 - 87493660 on Build GRCm38
          UniGene ID:
          Mm.136217
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID MSS275640
          Size 20 nmol
          Availability Made To Order
          Catalog # 1320001
          Price Contact Us
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Ascl1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_008553.4 NP_032579.2 1 1150
          GenBank mRNA AK141866.1 - 1 1140
          AK143210.1 - 1 1151
          BC055748.1 - 1 672 6415061
          JX478273.1 - 1 578
          M95603.1 - 1 653

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Human: NM_004316, BC001638, L08424, BC031299, AK290539, and others.
          This siRNA also targets the following transcripts in Rat: NM_022384, X53725.

          Panther Classification:

          Molecular Function -

          basic helix-loop-helix transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          neuron migration
          noradrenergic neuron development
          noradrenergic neuron fate commitment
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          Notch signaling pathway
          multicellular organism development
          regulation of mitotic cell cycle
          pattern specification process
          nervous system development
          neuroblast fate determination
          neuroblast proliferation
          regulation of Notch signaling pathway
          glial cell differentiation
          regulation of gene expression
          oligodendrocyte development
          spinal cord association neuron differentiation
          spinal cord oligodendrocyte cell differentiation
          spinal cord oligodendrocyte cell fate specification
          vestibular nucleus development
          oligodendrocyte cell fate commitment
          forebrain neuron differentiation
          commitment of neuronal cell to specific neuron type in forebrain
          central nervous system neuron development
          cerebral cortex development
          neurogenesis
          cell differentiation
          neuron differentiation
          regulation of epithelial cell differentiation
          regulation of cell proliferation
          negative regulation of apoptotic process
          positive regulation of neuron apoptotic process
          negative regulation of neuron differentiation
          positive regulation of neuron differentiation
          positive regulation of Notch signaling pathway
          positive regulation of cell cycle
          negative regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          cell maturation
          enteric nervous system development
          sympathetic nervous system development
          parasympathetic nervous system development
          neuron fate commitment
          neuron fate specification
          neuron development
          generation of neurons
          oligodendrocyte differentiation
          regulation of neurogenesis
          positive regulation of neurogenesis
          musculoskeletal movement, spinal reflex action
          subpallium neuron fate commitment
          regulation of timing of subpallium neuron differentiation
          olfactory pit development
          ventral spinal cord interneuron fate commitment
          lung neuroendocrine cell differentiation
          stomach neuroendocrine cell differentiation
          carotid body glomus cell differentiation
          adrenal chromaffin cell differentiation
          sympathetic ganglion development
          positive regulation of neural precursor cell proliferation
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          transcription factor activity, transcription factor binding
          transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
          DNA binding
          chromatin binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          protein homodimerization activity
          bHLH transcription factor binding
          sequence-specific DNA binding
          protein dimerization activity
          E-box binding

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