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          System Message

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          LOADING ...
          See other RAPGEF2 SIRNA Assays ›
          Gene Symbol:
          Rapgef2
          Gene Name:
          Rap guanine nucleotide exchange factor (GEF) 2
          Gene Aliases:
          5830453M24Rik, CNRasGEF, Pdzgef1, RA-GEF-1, mKIAA0313, nRapGEP
          Chromosome Location:
          Chr.3: 79062516 - 79287244 on Build GRCm38
          UniGene ID:
          Mm.31220
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID MSS293502
          Size 20 nmol
          Availability Made To Order
          Catalog # 1320001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Rapgef2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001099624.2 NP_001093094.2 21 3503
          GenBank mRNA AB093228.1 - 14 2386
          AK147368.1 - 21 3430
          BC067056.1 - 21 3503

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_001107684, XM_008761092, XM_008761093, XM_008761095, XM_006232511, and others.

          Panther Classification:

          Molecular Function -

          guanyl-nucleotide exchange factor

          Gene Ontology Categories:

          Function(s) Process(es)

          blood vessel development
          neuron migration
          signal transduction
          G-protein coupled receptor signaling pathway
          neuropeptide signaling pathway
          small GTPase mediated signal transduction
          multicellular organism development
          nervous system development
          negative regulation of cell proliferation
          positive regulation of neuron projection development
          cAMP-mediated signaling
          ventricular system development
          forebrain neuron development
          microvillus assembly
          cell differentiation
          neuron projection development
          brain-derived neurotrophic factor receptor signaling pathway
          positive regulation of protein binding
          Rap protein signal transduction
          nerve growth factor signaling pathway
          positive regulation of GTPase activity
          positive regulation of cAMP-mediated signaling
          positive regulation of protein kinase activity
          negative regulation of melanin biosynthetic process
          regulation of synaptic plasticity
          negative regulation of dendrite morphogenesis
          establishment of endothelial barrier
          positive regulation of ERK1 and ERK2 cascade
          cellular response to cAMP
          cellular response to cGMP
          adenylate cyclase-activating adrenergic receptor signaling pathway
          protein localization to plasma membrane
          establishment of endothelial intestinal barrier
          regulation of cell junction assembly
          cellular response to nerve growth factor stimulus
          positive regulation of cAMP-dependent protein kinase activity
          positive regulation of dendritic cell apoptotic process
          positive regulation of vasculogenesis
          positive regulation of neuron migration
          guanyl-nucleotide exchange factor activity
          Ras guanyl-nucleotide exchange factor activity
          GTPase activator activity
          Rap guanyl-nucleotide exchange factor activity
          protein kinase binding
          PDZ domain binding
          beta-1 adrenergic receptor binding
          WW domain binding
          phosphatidic acid binding

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