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          System Message

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          LOADING ...
          See other PTPN1 SIRNA Assays ›
          Gene Symbol:
          PTPN1
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 1
          Gene Aliases:
          PTP1B
          Chromosome Location:
          Chr.20: 50510321 - 50584762 on Build GRCh38
          UniGene ID:
          Hs.417549
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID VHS41290
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PTPN1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001278618.1 NP_001265547.1 2 285
          NM_002827.3 NP_002818.1 3 376
          GenBank mRNA AK290638.1 - 3 343
          AK299830.1 - 2 223
          AK316563.1 - 3 318
          AU117677.1 - 3 343
          BC015660.2 - 3 305 4844022
          BC018164.1 - 3 286 4338750
          BT006752.1 - 3 169
          DC300354.1 - 3 376
          M31724.1 - 3 259
          M33689.1 - 3 241

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          More Information


          Panther Classification:

          Molecular Function -

          protein phosphatase

          Gene Ontology Categories:

          Function(s) Process(es)

          protein dephosphorylation
          activation of signaling protein activity involved in unfolded protein response
          activation of JUN kinase activity
          insulin receptor signaling pathway
          regulation of signal transduction
          negative regulation of signal transduction
          regulation of endocytosis
          negative regulation of vascular endothelial growth factor receptor signaling pathway
          endoplasmic reticulum unfolded protein response
          actin cytoskeleton reorganization
          regulation of intracellular protein transport
          peptidyl-tyrosine dephosphorylation
          platelet-derived growth factor receptor-beta signaling pathway
          IRE1-mediated unfolded protein response
          negative regulation of MAP kinase activity
          negative regulation of insulin receptor signaling pathway
          regulation of type I interferon-mediated signaling pathway
          JAK-STAT cascade involved in growth hormone signaling pathway
          positive regulation of protein tyrosine kinase activity
          negative regulation of ERK1 and ERK2 cascade
          cell-cell adhesion
          regulation of hepatocyte growth factor receptor signaling pathway
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          positive regulation of IRE1-mediated unfolded protein response
          negative regulation of PERK-mediated unfolded protein response
          peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
          positive regulation of receptor catabolic process
          protein tyrosine phosphatase activity
          insulin receptor binding
          protein binding
          zinc ion binding
          enzyme binding
          protein kinase binding
          receptor tyrosine kinase binding
          poly(A) RNA binding
          ephrin receptor binding
          protein phosphatase 2A binding
          cadherin binding involved in cell-cell adhesion

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